FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1973648832> ?p ?o ?g. }

• W1973648832 endingPage "1175" @default.
• W1973648832 startingPage "1163" @default.
• W1973648832 abstract "The formation of thick filaments in striated muscle involves the chaperones Hsp90a and Unc45. We show that Unc45b and Hsp90a, two zebrafish orthologues, colocalize with myosin during myofibrillogenesis and associate with the Z line when myofibril assembly is completed. In response to stress or damage to the myofiber, Unc45b and Hsp90a dissociate from the Z line and transiently associate with myosin. Although chaperone activity of Unc45b requires the full-length protein, only the central and Unc45-Cro1p-She4p domains are required to anchor it to the Z line, and multiple subdomains mediate association with nascent myosin. We propose that the Z line serves as a reservoir for chaperones, allowing a rapid mobilization in response to muscle damage. Our data are consistent with a differential affinity model as an explanation for the shuttling of the chaperones between the Z line and myosin." @default.
• W1973648832 created "2016-06-24" @default.
• W1973648832 creator A5051508866 @default.
• W1973648832 creator A5070654230 @default.
• W1973648832 creator A5078931117 @default.
• W1973648832 date "2008-03-17" @default.
• W1973648832 modified "2023-10-14" @default.
• W1973648832 title "Shuttling of the chaperones Unc45b and Hsp90a between the A band and the Z line of the myofibril" @default.
• W1973648832 cites W1549888790 @default.
• W1973648832 cites W1574581708 @default.
• W1973648832 cites W1920281557 @default.
• W1973648832 cites W1946056901 @default.
• W1973648832 cites W1968203528 @default.
• W1973648832 cites W1973015668 @default.
• W1973648832 cites W1976976020 @default.
• W1973648832 cites W1983689793 @default.
• W1973648832 cites W1987448636 @default.
• W1973648832 cites W1987594760 @default.
• W1973648832 cites W1998342895 @default.
• W1973648832 cites W2003585900 @default.
• W1973648832 cites W2004925961 @default.
• W1973648832 cites W2009012143 @default.
• W1973648832 cites W2010206624 @default.
• W1973648832 cites W2023253519 @default.
• W1973648832 cites W2042297292 @default.
• W1973648832 cites W2046038671 @default.
• W1973648832 cites W2046044279 @default.
• W1973648832 cites W2046578630 @default.
• W1973648832 cites W2047503478 @default.
• W1973648832 cites W2079763949 @default.
• W1973648832 cites W2084483488 @default.
• W1973648832 cites W2084858513 @default.
• W1973648832 cites W2092516536 @default.
• W1973648832 cites W2096966529 @default.
• W1973648832 cites W2099269199 @default.
• W1973648832 cites W2118734144 @default.
• W1973648832 cites W2133484500 @default.
• W1973648832 cites W2133680467 @default.
• W1973648832 cites W2145828848 @default.
• W1973648832 cites W2157894871 @default.
• W1973648832 cites W2160147761 @default.
• W1973648832 cites W2162017609 @default.
• W1973648832 cites W2186787960 @default.
• W1973648832 cites W2403679102 @default.
• W1973648832 doi "https://doi.org/10.1083/jcb.200709128" @default.
• W1973648832 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2290844" @default.
• W1973648832 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18347070" @default.
• W1973648832 hasPublicationYear "2008" @default.
• W1973648832 type Work @default.
• W1973648832 sameAs 1973648832 @default.
• W1973648832 citedByCount "81" @default.
• W1973648832 countsByYear W19736488322012 @default.
• W1973648832 countsByYear W19736488322013 @default.
• W1973648832 countsByYear W19736488322014 @default.
• W1973648832 countsByYear W19736488322015 @default.
• W1973648832 countsByYear W19736488322016 @default.
• W1973648832 countsByYear W19736488322017 @default.
• W1973648832 countsByYear W19736488322018 @default.
• W1973648832 countsByYear W19736488322019 @default.
• W1973648832 countsByYear W19736488322020 @default.
• W1973648832 countsByYear W19736488322021 @default.
• W1973648832 countsByYear W19736488322022 @default.
• W1973648832 countsByYear W19736488322023 @default.
• W1973648832 crossrefType "journal-article" @default.
• W1973648832 hasAuthorship W1973648832A5051508866 @default.
• W1973648832 hasAuthorship W1973648832A5070654230 @default.
• W1973648832 hasAuthorship W1973648832A5078931117 @default.
• W1973648832 hasBestOaLocation W19736488321 @default.
• W1973648832 hasConcept C104317684 @default.
• W1973648832 hasConcept C105702510 @default.
• W1973648832 hasConcept C142724271 @default.
• W1973648832 hasConcept C15954220 @default.
• W1973648832 hasConcept C174054327 @default.
• W1973648832 hasConcept C207200792 @default.
• W1973648832 hasConcept C2775962898 @default.
• W1973648832 hasConcept C2776050358 @default.
• W1973648832 hasConcept C2776878037 @default.
• W1973648832 hasConcept C40209533 @default.
• W1973648832 hasConcept C55493867 @default.
• W1973648832 hasConcept C6997183 @default.
• W1973648832 hasConcept C71924100 @default.
• W1973648832 hasConcept C7301908 @default.
• W1973648832 hasConcept C8035138 @default.
• W1973648832 hasConcept C86803240 @default.
• W1973648832 hasConcept C95444343 @default.
• W1973648832 hasConceptScore W1973648832C104317684 @default.
• W1973648832 hasConceptScore W1973648832C105702510 @default.
• W1973648832 hasConceptScore W1973648832C142724271 @default.
• W1973648832 hasConceptScore W1973648832C15954220 @default.
• W1973648832 hasConceptScore W1973648832C174054327 @default.
• W1973648832 hasConceptScore W1973648832C207200792 @default.
• W1973648832 hasConceptScore W1973648832C2775962898 @default.
• W1973648832 hasConceptScore W1973648832C2776050358 @default.
• W1973648832 hasConceptScore W1973648832C2776878037 @default.
• W1973648832 hasConceptScore W1973648832C40209533 @default.
• W1973648832 hasConceptScore W1973648832C55493867 @default.
• W1973648832 hasConceptScore W1973648832C6997183 @default.
• W1973648832 hasConceptScore W1973648832C71924100 @default.

• next