Matches in SemOpenAlex for { <https://semopenalex.org/work/W1973664590> ?p ?o ?g. }
- W1973664590 endingPage "e71603" @default.
- W1973664590 startingPage "e71603" @default.
- W1973664590 abstract "Transient receptor potential channel ankryn 1 (TRPA1) expressed in the gastrointestinal tract is associated with gastric motility, gastric emptying, and food intake. In this study, we investigated the effects of methyl syringate, a specific and selective TRPA1 agonist, on food intake, gastric emptying, and gut hormone levels in imprinting control region (ICR) mice. The administration of methyl syringate suppressed cumulative food intake and gastric emptying. In addition, treatment with ruthenium red (RR), a general cation channel blocker, and HC-030031, a selective TRPA1 antagonist, inhibited methyl syringate-induced reduction of food intake and delayed gastric emptying in ICR mice. Methyl syringate also increased plasma peptide YY (PYY) levels, but not glucagon-like peptide-1 (GLP-1) levels. The elevation in PYY was blocked by treatment with RR and HC-030031. The present findings indicate that methyl syringate regulates food intake and gastric emptying through a TRPA1-mediated pathway and, by extension, can contribute to weight suppression." @default.
- W1973664590 created "2016-06-24" @default.
- W1973664590 creator A5003447522 @default.
- W1973664590 creator A5027381296 @default.
- W1973664590 creator A5031530694 @default.
- W1973664590 creator A5044663575 @default.
- W1973664590 creator A5052152109 @default.
- W1973664590 creator A5081134743 @default.
- W1973664590 date "2013-08-21" @default.
- W1973664590 modified "2023-09-29" @default.
- W1973664590 title "The TRPA1 Agonist, Methyl Syringate Suppresses Food Intake and Gastric Emptying" @default.
- W1973664590 cites W1482009781 @default.
- W1973664590 cites W1554456865 @default.
- W1973664590 cites W1964472706 @default.
- W1973664590 cites W1966740493 @default.
- W1973664590 cites W1982177336 @default.
- W1973664590 cites W2003265053 @default.
- W1973664590 cites W2009967312 @default.
- W1973664590 cites W2010165261 @default.
- W1973664590 cites W2012757513 @default.
- W1973664590 cites W2016732441 @default.
- W1973664590 cites W2017627887 @default.
- W1973664590 cites W2020833052 @default.
- W1973664590 cites W2022468655 @default.
- W1973664590 cites W2024412544 @default.
- W1973664590 cites W2033706801 @default.
- W1973664590 cites W2035257142 @default.
- W1973664590 cites W2048142422 @default.
- W1973664590 cites W2049332877 @default.
- W1973664590 cites W2052482154 @default.
- W1973664590 cites W2056934377 @default.
- W1973664590 cites W2065962602 @default.
- W1973664590 cites W2066505423 @default.
- W1973664590 cites W2074566221 @default.
- W1973664590 cites W2082113374 @default.
- W1973664590 cites W2091685843 @default.
- W1973664590 cites W2096459471 @default.
- W1973664590 cites W2097424825 @default.
- W1973664590 cites W2121712141 @default.
- W1973664590 cites W2129326126 @default.
- W1973664590 cites W2156316935 @default.
- W1973664590 cites W2157456431 @default.
- W1973664590 cites W2157748967 @default.
- W1973664590 cites W2164961795 @default.
- W1973664590 cites W2326347500 @default.
- W1973664590 doi "https://doi.org/10.1371/journal.pone.0071603" @default.
- W1973664590 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3749221" @default.
- W1973664590 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23990963" @default.
- W1973664590 hasPublicationYear "2013" @default.
- W1973664590 type Work @default.
- W1973664590 sameAs 1973664590 @default.
- W1973664590 citedByCount "42" @default.
- W1973664590 countsByYear W19736645902014 @default.
- W1973664590 countsByYear W19736645902015 @default.
- W1973664590 countsByYear W19736645902016 @default.
- W1973664590 countsByYear W19736645902017 @default.
- W1973664590 countsByYear W19736645902018 @default.
- W1973664590 countsByYear W19736645902019 @default.
- W1973664590 countsByYear W19736645902020 @default.
- W1973664590 countsByYear W19736645902021 @default.
- W1973664590 countsByYear W19736645902022 @default.
- W1973664590 countsByYear W19736645902023 @default.
- W1973664590 crossrefType "journal-article" @default.
- W1973664590 hasAuthorship W1973664590A5003447522 @default.
- W1973664590 hasAuthorship W1973664590A5027381296 @default.
- W1973664590 hasAuthorship W1973664590A5031530694 @default.
- W1973664590 hasAuthorship W1973664590A5044663575 @default.
- W1973664590 hasAuthorship W1973664590A5052152109 @default.
- W1973664590 hasAuthorship W1973664590A5081134743 @default.
- W1973664590 hasBestOaLocation W19736645901 @default.
- W1973664590 hasConcept C118303440 @default.
- W1973664590 hasConcept C126322002 @default.
- W1973664590 hasConcept C134018914 @default.
- W1973664590 hasConcept C155164980 @default.
- W1973664590 hasConcept C170493617 @default.
- W1973664590 hasConcept C185592680 @default.
- W1973664590 hasConcept C2776398474 @default.
- W1973664590 hasConcept C2776885963 @default.
- W1973664590 hasConcept C2777180221 @default.
- W1973664590 hasConcept C2778938600 @default.
- W1973664590 hasConcept C2779422922 @default.
- W1973664590 hasConcept C2780796126 @default.
- W1973664590 hasConcept C3020479747 @default.
- W1973664590 hasConcept C555293320 @default.
- W1973664590 hasConcept C71924100 @default.
- W1973664590 hasConcept C93984277 @default.
- W1973664590 hasConceptScore W1973664590C118303440 @default.
- W1973664590 hasConceptScore W1973664590C126322002 @default.
- W1973664590 hasConceptScore W1973664590C134018914 @default.
- W1973664590 hasConceptScore W1973664590C155164980 @default.
- W1973664590 hasConceptScore W1973664590C170493617 @default.
- W1973664590 hasConceptScore W1973664590C185592680 @default.
- W1973664590 hasConceptScore W1973664590C2776398474 @default.
- W1973664590 hasConceptScore W1973664590C2776885963 @default.
- W1973664590 hasConceptScore W1973664590C2777180221 @default.
- W1973664590 hasConceptScore W1973664590C2778938600 @default.
- W1973664590 hasConceptScore W1973664590C2779422922 @default.
- W1973664590 hasConceptScore W1973664590C2780796126 @default.