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- W1973669148 abstract "The dopamine hypothesis has been the major pathophysiological theory of psychosis in recent decades. Molecular imaging studies have provided in vivo evidence of increased dopamine synaptic availability and increased presynaptic dopamine synthesis in the striata of people with psychotic illnesses. These studies support the predictions of the dopamine hypothesis, but it remains to be determined whether dopaminergic abnormalities pre-date or are secondary to the development of psychosis. We selectively review the molecular imaging studies of the striatal dopaminergic system in psychosis and link this to models of psychosis and the functional subdivisions of the striatum to make predictions for the dopaminergic system in the prodromal phase of psychosis." @default.
- W1973669148 created "2016-06-24" @default.
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- W1973669148 date "2007-12-01" @default.
- W1973669148 modified "2023-10-01" @default.
- W1973669148 title "Molecular imaging studies of the striatal dopaminergic system in psychosis and predictions for the prodromal phase of psychosis" @default.
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- W1973669148 doi "https://doi.org/10.1192/bjp.191.51.s13" @default.
- W1973669148 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3796874" @default.
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- W1973669148 hasPublicationYear "2007" @default.
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