FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1973673423> ?p ?o ?g. }

• W1973673423 endingPage "733" @default.
• W1973673423 startingPage "727" @default.
• W1973673423 abstract "In Brief OBJECTIVE: To provide clinicians with information about the accuracy of real-time polymerase chain reaction (PCR) analysis of amniotic fluid for the prenatal diagnosis of congenital Toxoplasma infection. METHODS: This was a prospective cohort study of women with Toxoplasma infection identified by prenatal screening in three centers routinely carrying out real-time PCR for the detection of Toxoplasma gondii in amniotic fluid. The data available were gestational age at maternal infection, types and dates of maternal treatment, results of amniocentesis and neonatal work-up and definitive infectious status of the child. We estimated sensitivity, specificity and positive and negative predictive values both overall and per trimester of pregnancy at the time of maternal infection. RESULTS: Polymerase chain reaction analysis was carried out on amniotic fluid for 261 of the 377 patients included (69%). It was accurate with the exception of four negative results in children who were infected. Overall sensitivity and negative predictive value were 92.2% (95% confidence interval [CI] 81–98%) and 98.1% (95% CI 95–99.5%), respectively. There was no significant association with the trimester of pregnancy during which maternal infection occurred. Specificity and positive predictive values of 100% were obtained for all trimesters. CONCLUSION: Real-time PCR analysis significantly improves the detection of T. gondii on amniotic fluid. It provides an accurate tool to predict fetal infection and to decide on appropriate treatment and surveillance. However, postnatal follow-up remains necessary in the first year of life to fully exclude infection in children for whom PCR results were negative. LEVEL OF EVIDENCE: III Real-time polymerase chain reaction analysis of amniotic fluid is a useful tool for detecting Toxoplasma infection in fetuses." @default.
• W1973673423 created "2016-06-24" @default.
• W1973673423 creator A5003412641 @default.
• W1973673423 creator A5009459083 @default.
• W1973673423 creator A5021708731 @default.
• W1973673423 creator A5025913678 @default.
• W1973673423 creator A5049602497 @default.
• W1973673423 creator A5054570759 @default.
• W1973673423 creator A5081569122 @default.
• W1973673423 date "2010-04-01" @default.
• W1973673423 modified "2023-10-15" @default.
• W1973673423 title "Accuracy of Real-Time Polymerase Chain Reaction for Toxoplasma gondii in Amniotic Fluid" @default.
• W1973673423 cites W1592769832 @default.
• W1973673423 cites W1889288769 @default.
• W1973673423 cites W1977341255 @default.
• W1973673423 cites W2027109744 @default.
• W1973673423 cites W2043197861 @default.
• W1973673423 cites W2048281341 @default.
• W1973673423 cites W2049855073 @default.
• W1973673423 cites W2053572795 @default.
• W1973673423 cites W2066104965 @default.
• W1973673423 cites W2071159181 @default.
• W1973673423 cites W2085519018 @default.
• W1973673423 cites W2102747376 @default.
• W1973673423 cites W2109234405 @default.
• W1973673423 cites W2120196021 @default.
• W1973673423 cites W2125205431 @default.
• W1973673423 cites W2135553818 @default.
• W1973673423 cites W2163493873 @default.
• W1973673423 cites W2167681684 @default.
• W1973673423 cites W2168074927 @default.
• W1973673423 doi "https://doi.org/10.1097/aog.0b013e3181d57b09" @default.
• W1973673423 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20308831" @default.
• W1973673423 hasPublicationYear "2010" @default.
• W1973673423 type Work @default.
• W1973673423 sameAs 1973673423 @default.
• W1973673423 citedByCount "91" @default.
• W1973673423 countsByYear W19736734232012 @default.
• W1973673423 countsByYear W19736734232013 @default.
• W1973673423 countsByYear W19736734232014 @default.
• W1973673423 countsByYear W19736734232015 @default.
• W1973673423 countsByYear W19736734232016 @default.
• W1973673423 countsByYear W19736734232017 @default.
• W1973673423 countsByYear W19736734232018 @default.
• W1973673423 countsByYear W19736734232019 @default.
• W1973673423 countsByYear W19736734232020 @default.
• W1973673423 countsByYear W19736734232021 @default.
• W1973673423 countsByYear W19736734232022 @default.
• W1973673423 countsByYear W19736734232023 @default.
• W1973673423 crossrefType "journal-article" @default.
• W1973673423 hasAuthorship W1973673423A5003412641 @default.
• W1973673423 hasAuthorship W1973673423A5009459083 @default.
• W1973673423 hasAuthorship W1973673423A5021708731 @default.
• W1973673423 hasAuthorship W1973673423A5025913678 @default.
• W1973673423 hasAuthorship W1973673423A5049602497 @default.
• W1973673423 hasAuthorship W1973673423A5054570759 @default.
• W1973673423 hasAuthorship W1973673423A5081569122 @default.
• W1973673423 hasBestOaLocation W19736734231 @default.
• W1973673423 hasConcept C104317684 @default.
• W1973673423 hasConcept C126322002 @default.
• W1973673423 hasConcept C131872663 @default.
• W1973673423 hasConcept C159654299 @default.
• W1973673423 hasConcept C172680121 @default.
• W1973673423 hasConcept C188816634 @default.
• W1973673423 hasConcept C203014093 @default.
• W1973673423 hasConcept C2777966818 @default.
• W1973673423 hasConcept C2778128430 @default.
• W1973673423 hasConcept C2778194526 @default.
• W1973673423 hasConcept C2778258057 @default.
• W1973673423 hasConcept C2778376644 @default.
• W1973673423 hasConcept C2779234561 @default.
• W1973673423 hasConcept C3019719930 @default.
• W1973673423 hasConcept C44249647 @default.
• W1973673423 hasConcept C48023723 @default.
• W1973673423 hasConcept C49105822 @default.
• W1973673423 hasConcept C53789813 @default.
• W1973673423 hasConcept C54355233 @default.
• W1973673423 hasConcept C55493867 @default.
• W1973673423 hasConcept C71924100 @default.
• W1973673423 hasConcept C86803240 @default.
• W1973673423 hasConceptScore W1973673423C104317684 @default.
• W1973673423 hasConceptScore W1973673423C126322002 @default.
• W1973673423 hasConceptScore W1973673423C131872663 @default.
• W1973673423 hasConceptScore W1973673423C159654299 @default.
• W1973673423 hasConceptScore W1973673423C172680121 @default.
• W1973673423 hasConceptScore W1973673423C188816634 @default.
• W1973673423 hasConceptScore W1973673423C203014093 @default.
• W1973673423 hasConceptScore W1973673423C2777966818 @default.
• W1973673423 hasConceptScore W1973673423C2778128430 @default.
• W1973673423 hasConceptScore W1973673423C2778194526 @default.
• W1973673423 hasConceptScore W1973673423C2778258057 @default.
• W1973673423 hasConceptScore W1973673423C2778376644 @default.
• W1973673423 hasConceptScore W1973673423C2779234561 @default.
• W1973673423 hasConceptScore W1973673423C3019719930 @default.
• W1973673423 hasConceptScore W1973673423C44249647 @default.
• W1973673423 hasConceptScore W1973673423C48023723 @default.
• W1973673423 hasConceptScore W1973673423C49105822 @default.
• W1973673423 hasConceptScore W1973673423C53789813 @default.

• next