FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1973686872> ?p ?o ?g. }

• W1973686872 abstract "Despite intensive search for the optimal combination chemotherapy for aggressive non-Hodgkin's lymphoma (NHL), the CHOP (cyclophosphamide, adriamycin, vincristine and prednisolone) regimen is still the standard therapy. We investigated the clinical efficacy of a new combination regimen consisting of vincristine, bleomycin-cyclophosphamide, adriamycin, etoposide and prednisolone (VB-CHEP) in patients with aggressive NHL. A total of 29 patients with aggressive NHL was enrolled into the protocol. Eight patients were consolidated with cisplatin and cytarabine and 5 patients received radiotherapy for bulky disease. Objective response was achieved in 82.8% of the patients. Complete remission (CR) and partial remission rates were 72.4%, and 10.3%, respectively. CR rate was significantly lower in patients with advanced stage, extranodal disease and bone marrow involvement. Median follow-up time is 34+ months; 17 patients are disease-free while 12 died and only 2 patients with CR have relapsed so far. Median response duration is 29+ months and the median survival is 48+ months. The survival rate is 69% in the first year and 66% in the second year. A total of 152 cycles were evaluated for toxicity. Major hematological toxicity was myelosuppression and neutropenia, detected in 50.65%, was mostly grades 1-2. Neutropenic fever occurred in only 11 cycles. The side effects of the consolidation therapy were also acceptable. We conclude that the VB-CHEP regimen with consolidation therapy for high-risk patients may be an effective treatment for advanced stage aggressive NHL." @default.
• W1973686872 created "2016-06-24" @default.
• W1973686872 creator A5002704374 @default.
• W1973686872 creator A5008519096 @default.
• W1973686872 creator A5017541582 @default.
• W1973686872 creator A5023451058 @default.
• W1973686872 creator A5029938717 @default.
• W1973686872 creator A5030366726 @default.
• W1973686872 creator A5039543011 @default.
• W1973686872 creator A5061860445 @default.
• W1973686872 creator A5076720762 @default.
• W1973686872 creator A5078684819 @default.
• W1973686872 creator A5083841631 @default.
• W1973686872 date "2009-04-24" @default.
• W1973686872 modified "2023-10-17" @default.
• W1973686872 title "VB-CHEP chemotherapy regimen for aggressive non-Hodgkin's lymphomas" @default.
• W1973686872 cites W1896652710 @default.
• W1973686872 cites W1923785083 @default.
• W1973686872 cites W1995586052 @default.
• W1973686872 cites W2020893327 @default.
• W1973686872 cites W2026340406 @default.
• W1973686872 cites W2048488232 @default.
• W1973686872 cites W2073151455 @default.
• W1973686872 cites W2087824134 @default.
• W1973686872 cites W2154402133 @default.
• W1973686872 cites W2243140240 @default.
• W1973686872 cites W2255096282 @default.
• W1973686872 cites W2318772898 @default.
• W1973686872 cites W2334996101 @default.
• W1973686872 cites W3024436806 @default.
• W1973686872 doi "https://doi.org/10.1111/j.1600-0609.1998.tb01712.x" @default.
• W1973686872 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9820633" @default.
• W1973686872 hasPublicationYear "2009" @default.
• W1973686872 type Work @default.
• W1973686872 sameAs 1973686872 @default.
• W1973686872 citedByCount "3" @default.
• W1973686872 crossrefType "journal-article" @default.
• W1973686872 hasAuthorship W1973686872A5002704374 @default.
• W1973686872 hasAuthorship W1973686872A5008519096 @default.
• W1973686872 hasAuthorship W1973686872A5017541582 @default.
• W1973686872 hasAuthorship W1973686872A5023451058 @default.
• W1973686872 hasAuthorship W1973686872A5029938717 @default.
• W1973686872 hasAuthorship W1973686872A5030366726 @default.
• W1973686872 hasAuthorship W1973686872A5039543011 @default.
• W1973686872 hasAuthorship W1973686872A5061860445 @default.
• W1973686872 hasAuthorship W1973686872A5076720762 @default.
• W1973686872 hasAuthorship W1973686872A5078684819 @default.
• W1973686872 hasAuthorship W1973686872A5083841631 @default.
• W1973686872 hasConcept C126322002 @default.
• W1973686872 hasConcept C141071460 @default.
• W1973686872 hasConcept C2776694085 @default.
• W1973686872 hasConcept C2776715498 @default.
• W1973686872 hasConcept C2776755627 @default.
• W1973686872 hasConcept C2777063308 @default.
• W1973686872 hasConcept C2778041864 @default.
• W1973686872 hasConcept C2778119113 @default.
• W1973686872 hasConcept C2778476748 @default.
• W1973686872 hasConcept C2779338263 @default.
• W1973686872 hasConcept C2779429289 @default.
• W1973686872 hasConcept C2779725641 @default.
• W1973686872 hasConcept C2780653079 @default.
• W1973686872 hasConcept C2780873365 @default.
• W1973686872 hasConcept C2781214270 @default.
• W1973686872 hasConcept C2781413609 @default.
• W1973686872 hasConcept C2909463153 @default.
• W1973686872 hasConcept C71924100 @default.
• W1973686872 hasConcept C90924648 @default.
• W1973686872 hasConceptScore W1973686872C126322002 @default.
• W1973686872 hasConceptScore W1973686872C141071460 @default.
• W1973686872 hasConceptScore W1973686872C2776694085 @default.
• W1973686872 hasConceptScore W1973686872C2776715498 @default.
• W1973686872 hasConceptScore W1973686872C2776755627 @default.
• W1973686872 hasConceptScore W1973686872C2777063308 @default.
• W1973686872 hasConceptScore W1973686872C2778041864 @default.
• W1973686872 hasConceptScore W1973686872C2778119113 @default.
• W1973686872 hasConceptScore W1973686872C2778476748 @default.
• W1973686872 hasConceptScore W1973686872C2779338263 @default.
• W1973686872 hasConceptScore W1973686872C2779429289 @default.
• W1973686872 hasConceptScore W1973686872C2779725641 @default.
• W1973686872 hasConceptScore W1973686872C2780653079 @default.
• W1973686872 hasConceptScore W1973686872C2780873365 @default.
• W1973686872 hasConceptScore W1973686872C2781214270 @default.
• W1973686872 hasConceptScore W1973686872C2781413609 @default.
• W1973686872 hasConceptScore W1973686872C2909463153 @default.
• W1973686872 hasConceptScore W1973686872C71924100 @default.
• W1973686872 hasConceptScore W1973686872C90924648 @default.
• W1973686872 hasLocation W19736868721 @default.
• W1973686872 hasLocation W19736868722 @default.
• W1973686872 hasOpenAccess W1973686872 @default.
• W1973686872 hasPrimaryLocation W19736868721 @default.
• W1973686872 hasRelatedWork W1944400840 @default.
• W1973686872 hasRelatedWork W1973686872 @default.
• W1973686872 hasRelatedWork W2074448933 @default.
• W1973686872 hasRelatedWork W2084065914 @default.
• W1973686872 hasRelatedWork W2155734807 @default.
• W1973686872 hasRelatedWork W2158035792 @default.
• W1973686872 hasRelatedWork W2183352065 @default.
• W1973686872 hasRelatedWork W2342146492 @default.
• W1973686872 hasRelatedWork W2368204729 @default.
• W1973686872 hasRelatedWork W2435139026 @default.

• next