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• W1973688049 abstract "New analogues of cholecystokinin-7 (CCK-7) modified at amino acid residues 5 and 7 were assayed for their effect on gall bladder, pancreatic secretion, food intake (anorectic activity), amount of rearing (sedative activity) and analgesia, as well as their ability to inhibit 125I-CCK-8 binding to pancreatic cell membrane receptors and brain membrane receptors. The results were compared to the activities of standard compounds, CCK-8, cerulein, BOC-CCK-7 (BOC = tertbutyloxycarbonyl) and BOC-[Nle2,Nle5]CCK-7. All analogues exhibited agonistic effects. Their anorectic activity was significantly prolonged." @default.
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• W1973688049 date "1992-11-01" @default.
• W1973688049 modified "2023-10-02" @default.
• W1973688049 title "Pharmacological characterization of new cholecystokinin analogues" @default.
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• W1973688049 doi "https://doi.org/10.1016/0014-2999(92)90861-w" @default.
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