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• W1973696116 abstract "The glucose-14C uptakes (mg/gm/hour wet weight) for muscle fiber groups from 90-, 120-, and 150–160-day rhesus fetuses were similar. However, the glucose uptakes of muscle fiber groups from 2- to 6-week-old rhesus monkeys were slightly higher than those of the fetal series. Incubation under anoxic conditions increased glucose uptake by muscle from both fetal and infant monkeys. From the data on glucose uptakes and specific yields of lactate under aerobic and anaerobic conditions it is concluded that the ability of the fetus and neonate to survive anoxia is not explained by a greater response of the glycolytic enzymes of fetal and neonatal as compared to adult muscle during anaerobiosis. In all 3 fetal series the average ratios of specific yields for 14CO2 from glucose-1- and glucose-6-14C were significantly greater than 1.0, under both aerobic (1.5–2.0) and anaerobic conditions (3.8–4.0). In muscle from infant monkeys the ratios of specific yields for 14CO2 for the 2 substrates were not significantly greater than 1.0 under aerobic conditions, but under anaerobic conditions this ratio rose to 10. This data indicate that pentose cycle activity is more important in muscle from the fetal as compared with muscle from the infant monkey. However, when pentose cycle activity was estimated in relation to the total amount of glucose metabolized, less than 0.4% of the total glucose uptake was metabolized via this route." @default.
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• W1973696116 date "1966-11-01" @default.
• W1973696116 modified "2023-09-25" @default.
• W1973696116 title "Pentose cycle activity in muscle from fetal, neonatal and infant rhesus monkeys" @default.
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• W1973696116 doi "https://doi.org/10.1016/0003-9861(66)90413-9" @default.
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