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- W1973704623 abstract "The proportion and the distribution of wakefulness (W) slow-wave sleep (SWS) and paradoxical sleep (PS) were studied in 27-week-old rats over 24 hr periods, both in the fed state and after having been deprived of food for 2 to 3 weeks. In these rodents, prolonged fasting has been characterized by 3 successive metabolic phases which have been found to correspond to changes in protein metabolism. Sleep-waking changes were not studied during the first phase which was often of short duration (24 hr). During the second phase, i.e., when proteins were spared, the 24 hr proportions of W and sleep states remained unchanged. There were, however, profound changes in the daily mean episodic characteristics of each vigilance state (duration and frequency) except in the case of PS. During the phase II, the differences in the day/night proportions observed in each vigilance state were less than in the fed state. This reflected a lowering in the amplitude of their daily rhythms. In contrast, when protein use rose (phase III), W was increased sharply at the expense of SWS and PS, the latter being almost completely suppressed. During this last phase, which was also of short duration (by mean 3 days) alertness was greatly enhanced and the rats, which were typically nocturnal when fed, became diurnal. The changes in sleep and wakefulness were examined in relation to their effects on the homeostatic and cyclic components of sleep mechanisms and adaptative strategy to food deprivation in rat." @default.
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- W1973704623 date "1989-08-01" @default.
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- W1973704623 title "Sleep changes in fasting rats" @default.
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- W1973704623 doi "https://doi.org/10.1016/0031-9384(89)90252-7" @default.
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