FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1973706034> ?p ?o ?g. }

• W1973706034 endingPage "1077" @default.
• W1973706034 startingPage "1069" @default.
• W1973706034 abstract "The potential use of ultradeformable and standard liposomes as skin drug delivery systems was investigated in-vitro. An improved experimental design gave a good measure for skin deposition of drug. This avoided the contamination that can occur due to incomplete washing of the donor before direct determination of the amount of drug in the skin. The design used aqueous ethanolic receptor which is believed to diffuse into skin, disrupting deposited liposomes (if any) and thus releasing both bound and free drug. The receptor fluid was refined by testing different concentrations of ethanol. The applied dose was also optimized. Using the improved design and the optimum dose, an ultradeformable formulation was compared with four traditional liposomes for skin delivery of 5-fluorouracil (5-FU). The best receptor was 50% aqueous ethanol and the optimum dose was 20 microL. The ultradeformable formulation was superior to standard liposomes in the skin delivery of 5-FU. Of the traditional liposomes, the non-rigid preparation was the best. However, stabilization of the liposome membrane with cholesterol abolished the benefit of this non-rigid preparation. It was concluded that ultradeformable vesicles are promising agents for skin delivery of drugs." @default.
• W1973706034 created "2016-06-24" @default.
• W1973706034 creator A5022276762 @default.
• W1973706034 creator A5022568201 @default.
• W1973706034 creator A5087362532 @default.
• W1973706034 date "2001-08-01" @default.
• W1973706034 modified "2023-09-23" @default.
• W1973706034 title "Skin delivery of 5-fluorouracil from ultradeformable and standard liposomes in-vitro" @default.
• W1973706034 cites W1529934495 @default.
• W1973706034 cites W1576072987 @default.
• W1973706034 cites W1979512588 @default.
• W1973706034 cites W1986557490 @default.
• W1973706034 cites W198663981 @default.
• W1973706034 cites W1986758623 @default.
• W1973706034 cites W1989805532 @default.
• W1973706034 cites W1990107938 @default.
• W1973706034 cites W2007124382 @default.
• W1973706034 cites W2013009465 @default.
• W1973706034 cites W2016337768 @default.
• W1973706034 cites W2025129627 @default.
• W1973706034 cites W2031181473 @default.
• W1973706034 cites W2036424067 @default.
• W1973706034 cites W2039225121 @default.
• W1973706034 cites W2058945924 @default.
• W1973706034 cites W2065369943 @default.
• W1973706034 cites W2078062818 @default.
• W1973706034 cites W2079348676 @default.
• W1973706034 cites W2091247610 @default.
• W1973706034 cites W2094677265 @default.
• W1973706034 cites W2119223808 @default.
• W1973706034 cites W2137802295 @default.
• W1973706034 cites W2137902073 @default.
• W1973706034 cites W2141331305 @default.
• W1973706034 cites W2154802845 @default.
• W1973706034 cites W2165751567 @default.
• W1973706034 cites W2168089247 @default.
• W1973706034 cites W4237299381 @default.
• W1973706034 doi "https://doi.org/10.1211/0022357011776450" @default.
• W1973706034 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11518016" @default.
• W1973706034 hasPublicationYear "2001" @default.
• W1973706034 type Work @default.
• W1973706034 sameAs 1973706034 @default.
• W1973706034 citedByCount "187" @default.
• W1973706034 countsByYear W19737060342012 @default.
• W1973706034 countsByYear W19737060342013 @default.
• W1973706034 countsByYear W19737060342014 @default.
• W1973706034 countsByYear W19737060342015 @default.
• W1973706034 countsByYear W19737060342016 @default.
• W1973706034 countsByYear W19737060342017 @default.
• W1973706034 countsByYear W19737060342018 @default.
• W1973706034 countsByYear W19737060342019 @default.
• W1973706034 countsByYear W19737060342020 @default.
• W1973706034 countsByYear W19737060342021 @default.
• W1973706034 countsByYear W19737060342022 @default.
• W1973706034 countsByYear W19737060342023 @default.
• W1973706034 crossrefType "journal-article" @default.
• W1973706034 hasAuthorship W1973706034A5022276762 @default.
• W1973706034 hasAuthorship W1973706034A5022568201 @default.
• W1973706034 hasAuthorship W1973706034A5087362532 @default.
• W1973706034 hasBestOaLocation W19737060341 @default.
• W1973706034 hasConcept C130316041 @default.
• W1973706034 hasConcept C150903083 @default.
• W1973706034 hasConcept C178790620 @default.
• W1973706034 hasConcept C184651966 @default.
• W1973706034 hasConcept C185154212 @default.
• W1973706034 hasConcept C185592680 @default.
• W1973706034 hasConcept C202751555 @default.
• W1973706034 hasConcept C207001950 @default.
• W1973706034 hasConcept C2779820397 @default.
• W1973706034 hasConcept C2780035454 @default.
• W1973706034 hasConcept C2780161600 @default.
• W1973706034 hasConcept C41625074 @default.
• W1973706034 hasConcept C43617362 @default.
• W1973706034 hasConcept C55493867 @default.
• W1973706034 hasConcept C71924100 @default.
• W1973706034 hasConcept C86803240 @default.
• W1973706034 hasConcept C98274493 @default.
• W1973706034 hasConceptScore W1973706034C130316041 @default.
• W1973706034 hasConceptScore W1973706034C150903083 @default.
• W1973706034 hasConceptScore W1973706034C178790620 @default.
• W1973706034 hasConceptScore W1973706034C184651966 @default.
• W1973706034 hasConceptScore W1973706034C185154212 @default.
• W1973706034 hasConceptScore W1973706034C185592680 @default.
• W1973706034 hasConceptScore W1973706034C202751555 @default.
• W1973706034 hasConceptScore W1973706034C207001950 @default.
• W1973706034 hasConceptScore W1973706034C2779820397 @default.
• W1973706034 hasConceptScore W1973706034C2780035454 @default.
• W1973706034 hasConceptScore W1973706034C2780161600 @default.
• W1973706034 hasConceptScore W1973706034C41625074 @default.
• W1973706034 hasConceptScore W1973706034C43617362 @default.
• W1973706034 hasConceptScore W1973706034C55493867 @default.
• W1973706034 hasConceptScore W1973706034C71924100 @default.
• W1973706034 hasConceptScore W1973706034C86803240 @default.
• W1973706034 hasConceptScore W1973706034C98274493 @default.
• W1973706034 hasIssue "8" @default.
• W1973706034 hasLocation W19737060341 @default.
• W1973706034 hasLocation W19737060342 @default.
• W1973706034 hasOpenAccess W1973706034 @default.

• next