FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1973720960> ?p ?o ?g. }

• W1973720960 endingPage "3144" @default.
• W1973720960 startingPage "3139" @default.
• W1973720960 abstract "Traditional quantitative analysis of 24-h esophageal pH monitoring data does not include the pH of reflux episodes. Area under pH 4 (AU4) is a recently introduced parameter that describes the acid exposure rate through both duration and depth of pH falls.In Study A, we enrolled 20 healthy controls and 42 patients (18 without esophagitis, 24 with Savary I-III esophagitis) in a study evaluating reference values for 24-h reflux time at pH <4 (RT) and 24-h AU4 by means of receiver operating characteristic (ROC) discriminant analysis. For Study B, we next prospectively applied the resulting cutoffs to 16 healthy controls and to 110 gastroesophageal reflux (GERD) patients (55 with esophagitis) to adjust sensitivity, specificity, and predictive values of both RT and AU4.In Study A, the best cutoff values were 5.1% for RT (Area Index +/- SE, 0.899 +/- 0.038; 95% confidence interval [C.I.], 0.796 +/- 0.961) and 36.1 pH x min for AU4 (Area Index +/- SE, 0.935 +/- 0.03; 95% C.I., 0.842 +/- 0.981); AU4 gave the best performance (p = 0.038 vs RT) in discriminating controls and GERD patients. In Study B, RT was abnormal in three controls and 79 patients; AU4 identified all the controls and patients with abnormal RT and also 10/31 patients (32.3%) with so-called normal acid exposure (according to RT). In the whole GERD group of patients, AU4 and RT specificity was 81.2%, whereas sensitivity was 71.8% for RT and 80.9% for AU4 (chi2, 61.831; DF, 1; p < 0.005); PPV/NPV were 96.3%/29.5% for RT, and 96.7%/38.2% for AU4.AU4 appears to be a simple and sensitive quantitative parameter to measure the esophageal acid exposure in adults submitted to 24-h pH monitoring, and it could be an useful clinical aid in evaluating normal RT tests where, from a clinical point of view, a reflux disease is highly likely." @default.
• W1973720960 created "2016-06-24" @default.
• W1973720960 creator A5004299666 @default.
• W1973720960 creator A5069960175 @default.
• W1973720960 creator A5080767989 @default.
• W1973720960 creator A5088399709 @default.
• W1973720960 creator A5088890312 @default.
• W1973720960 date "1999-11-01" @default.
• W1973720960 modified "2023-09-27" @default.
• W1973720960 title "Area Under pH 4: A More Sensitive Parameter for The Quantitative Analysis of Esophageal Acid Exposure in Adults" @default.
• W1973720960 cites W1527897335 @default.
• W1973720960 cites W1568350882 @default.
• W1973720960 cites W1968114652 @default.
• W1973720960 cites W1974143591 @default.
• W1973720960 cites W1974496938 @default.
• W1973720960 cites W1992825216 @default.
• W1973720960 cites W2012249755 @default.
• W1973720960 cites W2016260325 @default.
• W1973720960 cites W2024219177 @default.
• W1973720960 cites W2046358040 @default.
• W1973720960 cites W2053081131 @default.
• W1973720960 cites W2074476123 @default.
• W1973720960 cites W2081620097 @default.
• W1973720960 cites W2089253770 @default.
• W1973720960 cites W2092996785 @default.
• W1973720960 cites W2102150307 @default.
• W1973720960 cites W2104960492 @default.
• W1973720960 cites W2154702608 @default.
• W1973720960 cites W2414362229 @default.
• W1973720960 cites W2883888396 @default.
• W1973720960 cites W3151306160 @default.
• W1973720960 cites W4236687661 @default.
• W1973720960 cites W4246768377 @default.
• W1973720960 doi "https://doi.org/10.1111/j.1572-0241.1999.01505.x" @default.
• W1973720960 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10566704" @default.
• W1973720960 hasPublicationYear "1999" @default.
• W1973720960 type Work @default.
• W1973720960 sameAs 1973720960 @default.
• W1973720960 citedByCount "13" @default.
• W1973720960 countsByYear W19737209602017 @default.
• W1973720960 crossrefType "journal-article" @default.
• W1973720960 hasAuthorship W1973720960A5004299666 @default.
• W1973720960 hasAuthorship W1973720960A5069960175 @default.
• W1973720960 hasAuthorship W1973720960A5080767989 @default.
• W1973720960 hasAuthorship W1973720960A5088399709 @default.
• W1973720960 hasAuthorship W1973720960A5088890312 @default.
• W1973720960 hasConcept C126322002 @default.
• W1973720960 hasConcept C141071460 @default.
• W1973720960 hasConcept C2777014526 @default.
• W1973720960 hasConcept C2779134260 @default.
• W1973720960 hasConcept C2779920096 @default.
• W1973720960 hasConcept C43270747 @default.
• W1973720960 hasConcept C44249647 @default.
• W1973720960 hasConcept C58471807 @default.
• W1973720960 hasConcept C71924100 @default.
• W1973720960 hasConcept C90924648 @default.
• W1973720960 hasConceptScore W1973720960C126322002 @default.
• W1973720960 hasConceptScore W1973720960C141071460 @default.
• W1973720960 hasConceptScore W1973720960C2777014526 @default.
• W1973720960 hasConceptScore W1973720960C2779134260 @default.
• W1973720960 hasConceptScore W1973720960C2779920096 @default.
• W1973720960 hasConceptScore W1973720960C43270747 @default.
• W1973720960 hasConceptScore W1973720960C44249647 @default.
• W1973720960 hasConceptScore W1973720960C58471807 @default.
• W1973720960 hasConceptScore W1973720960C71924100 @default.
• W1973720960 hasConceptScore W1973720960C90924648 @default.
• W1973720960 hasIssue "11" @default.
• W1973720960 hasLocation W19737209601 @default.
• W1973720960 hasLocation W19737209602 @default.
• W1973720960 hasOpenAccess W1973720960 @default.
• W1973720960 hasPrimaryLocation W19737209601 @default.
• W1973720960 hasRelatedWork W2077553504 @default.
• W1973720960 hasRelatedWork W2295989818 @default.
• W1973720960 hasRelatedWork W2347352957 @default.
• W1973720960 hasRelatedWork W2382072563 @default.
• W1973720960 hasRelatedWork W2384655150 @default.
• W1973720960 hasRelatedWork W2473047450 @default.
• W1973720960 hasRelatedWork W2611981396 @default.
• W1973720960 hasRelatedWork W3116896978 @default.
• W1973720960 hasRelatedWork W4254835069 @default.
• W1973720960 hasRelatedWork W4285154846 @default.
• W1973720960 hasVolume "94" @default.
• W1973720960 isParatext "false" @default.
• W1973720960 isRetracted "false" @default.
• W1973720960 magId "1973720960" @default.
• W1973720960 workType "article" @default.