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- W1973776052 abstract "Cardiac allograft vasculopathy remains a credible threat to long-term cardiac allograft survival. 1 Young J.B. Perspectives on cardiac allograft vasculopathy. Curr Atheroscler Rep. 2000; 2: 259-271 Crossref PubMed Scopus (20) Google Scholar During the years, this vexing dilemma has led investigators to seek ameliorative targets with little or no success. More recently, primary immunoprophylaxis strategies that use target of rapamycin (TOR) inhibitors have suggested a favorable influence on the early expression of cardiac allograft vasculopathy (intimal thickening). 2 Eisen H. Dorent R. Mancini D. et al. Safety and efficacy of everolimus (RAD) as part of a triple immunosuppressive regimen in de novo cardiac transplant recipients six month analysis (abstract). J Heart Lung Transplant. 2002; 21: 55 Abstract Full Text Full Text PDF PubMed Google Scholar , 3 Keogh A. Immunosuppression: an evolving art and science. TOR inhibitors. Rapamycin: results of a randomized trial following heart transplantation. Program and abstracts of the International Society for Heart and Lung Transplantation 22nd Annual Meeting and Scientific Sessions, April 10–13, 2002, Washington DC Google Scholar We wish to review the preliminary information surrounding this potential advance and to outline the inherent pitfalls in universally accepting these early findings." @default.
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- W1973776052 title "TOR inhibitors and cardiac allograft vasculopathy: is inhibition of intimal thickening an adequate surrogate of benefit?" @default.
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- W1973776052 doi "https://doi.org/10.1016/s1053-2498(02)00525-9" @default.
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