Matches in SemOpenAlex for { <https://semopenalex.org/work/W1973808700> ?p ?o ?g. }
- W1973808700 endingPage "33" @default.
- W1973808700 startingPage "24" @default.
- W1973808700 abstract "An ultra-sensitive LC method for the simultaneous quantitation of paracetamol, carbamazepine, losartan and ciprofloxacin have been developed and validated following the ICH guidelines at isobestic point and by programming the detector at individual wavelength of each component. The components were eluted by 50:50 v/v acetonitrile-water (pH 3.0) using a Bondapak, C18 (10 μm, 25 × 0.46 cm) column at flow rate of 1.0 mL·min-1 with detection wavelength 240 nm at isobestic point and 245, 230, 206 and 272 nm for paracetamol, carbamazepine, losartan potassium and ciprofloxacin respectively by programming the detector. Linearity was found to be 0.5 - 24, 0.25 - 8.0, 0.4 - 12 and 0.75 - 10 μg·mL-1 (R2 > 0.999) with detection limits 99, 20, 30 and 6.0 ng·mL-1 respectively. Comparison study with time program method showed more sensitivity with calibration range of 0.4 - 12, 0.2 - 6.0, 0.1 - 3.0 and 0.25 - 8.0 μg·mL-1 (R2 > 0.999) and LOD values 29, 11, 2.0 and 5.0 ng·mL-1 respectively. Percent recoveries >98.37% from pharmaceutical formulation and human serum samples and RSD 2% for inter-day and intra-day assay were obtained. The method was found to be robust and can be successfully applied for the determination of studied drugs in, pharmaceutical formulations and human serum without interference of excipients or endogenous components of serum." @default.
- W1973808700 created "2016-06-24" @default.
- W1973808700 creator A5026329945 @default.
- W1973808700 creator A5054652395 @default.
- W1973808700 creator A5060810030 @default.
- W1973808700 date "2013-01-01" @default.
- W1973808700 modified "2023-10-01" @default.
- W1973808700 title "An Ultra-sensitive LC Method for the Simultaneous Determination of Paracetamol, Carbamazepine, Losartan and Ciprofloxacin in Bulk Drug, Pharmaceutical Formulation and Human Serum by Programming the Detector" @default.
- W1973808700 cites W1606716825 @default.
- W1973808700 cites W1966248204 @default.
- W1973808700 cites W1967050019 @default.
- W1973808700 cites W1968316487 @default.
- W1973808700 cites W1974741524 @default.
- W1973808700 cites W1998511800 @default.
- W1973808700 cites W1999287990 @default.
- W1973808700 cites W2000659660 @default.
- W1973808700 cites W2003641589 @default.
- W1973808700 cites W2016507119 @default.
- W1973808700 cites W2021123817 @default.
- W1973808700 cites W2031427734 @default.
- W1973808700 cites W2038315749 @default.
- W1973808700 cites W2039492467 @default.
- W1973808700 cites W2040093848 @default.
- W1973808700 cites W2041244116 @default.
- W1973808700 cites W2048685411 @default.
- W1973808700 cites W2049079000 @default.
- W1973808700 cites W2052074371 @default.
- W1973808700 cites W2052958918 @default.
- W1973808700 cites W2059478235 @default.
- W1973808700 cites W2069739441 @default.
- W1973808700 cites W2076690405 @default.
- W1973808700 cites W2082649042 @default.
- W1973808700 cites W2084880750 @default.
- W1973808700 cites W2086668953 @default.
- W1973808700 cites W2094410508 @default.
- W1973808700 cites W2139545851 @default.
- W1973808700 cites W2148507435 @default.
- W1973808700 cites W2156135779 @default.
- W1973808700 cites W2171866765 @default.
- W1973808700 cites W2320058521 @default.
- W1973808700 cites W4211013529 @default.
- W1973808700 cites W4232918452 @default.
- W1973808700 doi "https://doi.org/10.4236/ajac.2013.41004" @default.
- W1973808700 hasPublicationYear "2013" @default.
- W1973808700 type Work @default.
- W1973808700 sameAs 1973808700 @default.
- W1973808700 citedByCount "17" @default.
- W1973808700 countsByYear W19738087002012 @default.
- W1973808700 countsByYear W19738087002013 @default.
- W1973808700 countsByYear W19738087002014 @default.
- W1973808700 countsByYear W19738087002015 @default.
- W1973808700 countsByYear W19738087002016 @default.
- W1973808700 countsByYear W19738087002017 @default.
- W1973808700 countsByYear W19738087002018 @default.
- W1973808700 countsByYear W19738087002019 @default.
- W1973808700 countsByYear W19738087002020 @default.
- W1973808700 crossrefType "journal-article" @default.
- W1973808700 hasAuthorship W1973808700A5026329945 @default.
- W1973808700 hasAuthorship W1973808700A5054652395 @default.
- W1973808700 hasAuthorship W1973808700A5060810030 @default.
- W1973808700 hasBestOaLocation W19738087001 @default.
- W1973808700 hasConcept C106186310 @default.
- W1973808700 hasConcept C118552586 @default.
- W1973808700 hasConcept C119128265 @default.
- W1973808700 hasConcept C170493617 @default.
- W1973808700 hasConcept C185592680 @default.
- W1973808700 hasConcept C2778186239 @default.
- W1973808700 hasConcept C2779253243 @default.
- W1973808700 hasConcept C2780288358 @default.
- W1973808700 hasConcept C2908929049 @default.
- W1973808700 hasConcept C2909209853 @default.
- W1973808700 hasConcept C43617362 @default.
- W1973808700 hasConcept C55493867 @default.
- W1973808700 hasConcept C71924100 @default.
- W1973808700 hasConceptScore W1973808700C106186310 @default.
- W1973808700 hasConceptScore W1973808700C118552586 @default.
- W1973808700 hasConceptScore W1973808700C119128265 @default.
- W1973808700 hasConceptScore W1973808700C170493617 @default.
- W1973808700 hasConceptScore W1973808700C185592680 @default.
- W1973808700 hasConceptScore W1973808700C2778186239 @default.
- W1973808700 hasConceptScore W1973808700C2779253243 @default.
- W1973808700 hasConceptScore W1973808700C2780288358 @default.
- W1973808700 hasConceptScore W1973808700C2908929049 @default.
- W1973808700 hasConceptScore W1973808700C2909209853 @default.
- W1973808700 hasConceptScore W1973808700C43617362 @default.
- W1973808700 hasConceptScore W1973808700C55493867 @default.
- W1973808700 hasConceptScore W1973808700C71924100 @default.
- W1973808700 hasIssue "01" @default.
- W1973808700 hasLocation W19738087001 @default.
- W1973808700 hasOpenAccess W1973808700 @default.
- W1973808700 hasPrimaryLocation W19738087001 @default.
- W1973808700 hasRelatedWork W2022172446 @default.
- W1973808700 hasRelatedWork W2024649627 @default.
- W1973808700 hasRelatedWork W2056461247 @default.
- W1973808700 hasRelatedWork W2114457478 @default.
- W1973808700 hasRelatedWork W2188027837 @default.
- W1973808700 hasRelatedWork W2349914492 @default.
- W1973808700 hasRelatedWork W3008236077 @default.