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- W1973809738 abstract "Abstract Subclones of the murine erythroleukemia cell line DS 19 with different sensitivities towards inhibition by dexamethasone (DEX) of the hexamethylene bisacetamide induced differentiation have been obtained. Scatchard analysis of DEX binding to whole cells and the time course of DEX binding to nuclei show that resistance to inhibition of erythrodifferentiation by DEX is neither associated with a reduction in specific binding of the hormone nor in a lack of activation or translocation to the nuclei of hormone receptor complexes. Hence resistance in these subclones must result from a defect at an event after binding of hormone-receptor complexes to chromatin if inhibition of differentiation is mediated by these complexes." @default.
- W1973809738 created "2016-06-24" @default.
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- W1973809738 date "1981-08-01" @default.
- W1973809738 modified "2023-09-23" @default.
- W1973809738 title "Comparison of dexamethasone binding and resistance to inhibition of induced differentiation in subclones of murine erythroleukemia cells" @default.
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- W1973809738 doi "https://doi.org/10.1016/0006-291x(81)91824-6" @default.
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- W1973809738 hasPublicationYear "1981" @default.
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