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- W1973885151 abstract "Cell fusion resulting in zygote giant cell formation is the first observable event of sexual development in D. discoideum. The results reported here show that this process is Ca2+-dependent and that by increasing the level of Ca2+ in the medium the number of cell fusions can be increased 57-fold over control cultures. The data also suggest that Ca2+ has both an early and late function in the development of zygotes and these functions are mediated at the cell surface. These results plus the availability of a liquid culture for generating large volumes of cells make sexual development in D. discoideum an excellent system for the analysis of membrane fusion in eukaryotes." @default.
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- W1973885151 date "1980-04-01" @default.
- W1973885151 modified "2023-09-24" @default.
- W1973885151 title "Ca2+ and cell fusion during sexual development in liquid cultures of Dictyostelium discoideum" @default.
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- W1973885151 doi "https://doi.org/10.1016/0014-4827(80)90298-0" @default.
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