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- W1973886143 abstract "We have shown previously that four of five white mutant alleles arising in P-M dysgenic hybrids result from the insertion of strongly homologous DNA sequence elements. We have named these P elements. We report that P elements are present in 30-50 copies per haploid genome in all P strains examined and apparently are missing entirely from all M strains examined, with one exception. Furthermore, members of the P family apparently transpose frequently in P-M dysgenic hybrids; chromosomes descendant from P-M dysgenic hybrids frequently show newly acquired P elements. Finally, the strain-specific breakpoint hotspots for the rearrangement of the pi 2 P X chromosome occurring in P-M dysgenic hybrids are apparently sites of residence of P elements. These observations strongly support the P factor hypothesis for the mechanistic basis of P-M hybrid dysgenesis." @default.
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- W1973886143 date "1982-07-01" @default.
- W1973886143 modified "2023-09-30" @default.
- W1973886143 title "The molecular basis of P-M hybrid dysgenesis: The role of the P element, a P-strain-specific transposon family" @default.
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- W1973886143 doi "https://doi.org/10.1016/0092-8674(82)90463-9" @default.
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