FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1973913077> ?p ?o ?g. }

• W1973913077 endingPage "139" @default.
• W1973913077 startingPage "132" @default.
• W1973913077 abstract "The regenerative capacity of viable cells remaining in cryopreserved vascular allografts is still unclear. Recently, the regenerating gene (REG) has been documented to play an important role in various regenerating tissues. Here we show the possibility of REG induction for the enhancement of cryopreserved vascular allograft viability. Cryopreserved rat aortae were isografted or allografted heterotopically. Fresh isografts were also tested. The transplants were retrieved 3, 6, 9, and 12 days after implantation and the intragraft REG mRNA was measured by a real-time quantitative reverse transcriptional polymerase chain reaction method. REG expression was not detected before implantation. REG expression in cryopreserved isografts gradually increased after transplantation, whereas in fresh isografts or cryopreserved allografts it decreased over time after initial expression. Daily administration of 0.5 g/kg nicotinamide (an agent known to be a potent inducer of REG) induced intragraft REG mRNA in cryopreserved allografts (p < 0.05) accompanied by augmentation of the intragraft cell population. Daily administration of 0.5 mg/kg FK506 (an immunosuppressant) induced intragraft REG mRNA both in cryopreserved isografts and allografts (p < 0.01). We conclude that REG-inductive therapy shows promise as a novel strategy for enhancing the viability of vascular allografts. Moreover, FK506 may be involved in tissue regeneration as well as immunosuppression." @default.
• W1973913077 created "2016-06-24" @default.
• W1973913077 creator A5004559621 @default.
• W1973913077 creator A5014822163 @default.
• W1973913077 creator A5016197065 @default.
• W1973913077 creator A5023464844 @default.
• W1973913077 creator A5024368247 @default.
• W1973913077 creator A5031853100 @default.
• W1973913077 creator A5049614598 @default.
• W1973913077 creator A5081633503 @default.
• W1973913077 creator A5036853621 @default.
• W1973913077 date "2003-01-01" @default.
• W1973913077 modified "2023-10-16" @default.
• W1973913077 title "Enhancement of Cell Viability in Cryopreserved Rat Vascular Grafts by Administration of Regenerating Gene <i>(Reg)</i> Inducers" @default.
• W1973913077 cites W1678997151 @default.
• W1973913077 cites W1965147716 @default.
• W1973913077 cites W1973864043 @default.
• W1973913077 cites W1997985320 @default.
• W1973913077 cites W2012266847 @default.
• W1973913077 cites W2020534111 @default.
• W1973913077 cites W2041963020 @default.
• W1973913077 cites W2090742029 @default.
• W1973913077 cites W2166350499 @default.
• W1973913077 cites W3022565661 @default.
• W1973913077 cites W4237789900 @default.
• W1973913077 cites W4242587817 @default.
• W1973913077 doi "https://doi.org/10.1159/000070710" @default.
• W1973913077 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12808349" @default.
• W1973913077 hasPublicationYear "2003" @default.
• W1973913077 type Work @default.
• W1973913077 sameAs 1973913077 @default.
• W1973913077 citedByCount "14" @default.
• W1973913077 countsByYear W19739130772013 @default.
• W1973913077 countsByYear W19739130772014 @default.
• W1973913077 countsByYear W19739130772015 @default.
• W1973913077 countsByYear W19739130772016 @default.
• W1973913077 countsByYear W19739130772017 @default.
• W1973913077 countsByYear W19739130772018 @default.
• W1973913077 countsByYear W19739130772019 @default.
• W1973913077 countsByYear W19739130772021 @default.
• W1973913077 countsByYear W19739130772022 @default.
• W1973913077 crossrefType "journal-article" @default.
• W1973913077 hasAuthorship W1973913077A5004559621 @default.
• W1973913077 hasAuthorship W1973913077A5014822163 @default.
• W1973913077 hasAuthorship W1973913077A5016197065 @default.
• W1973913077 hasAuthorship W1973913077A5023464844 @default.
• W1973913077 hasAuthorship W1973913077A5024368247 @default.
• W1973913077 hasAuthorship W1973913077A5031853100 @default.
• W1973913077 hasAuthorship W1973913077A5036853621 @default.
• W1973913077 hasAuthorship W1973913077A5049614598 @default.
• W1973913077 hasAuthorship W1973913077A5081633503 @default.
• W1973913077 hasConcept C104317684 @default.
• W1973913077 hasConcept C126322002 @default.
• W1973913077 hasConcept C1491633281 @default.
• W1973913077 hasConcept C150194340 @default.
• W1973913077 hasConcept C16685009 @default.
• W1973913077 hasConcept C171056886 @default.
• W1973913077 hasConcept C179933525 @default.
• W1973913077 hasConcept C196843134 @default.
• W1973913077 hasConcept C203014093 @default.
• W1973913077 hasConcept C2225953 @default.
• W1973913077 hasConcept C2911091166 @default.
• W1973913077 hasConcept C53227056 @default.
• W1973913077 hasConcept C55493867 @default.
• W1973913077 hasConcept C71924100 @default.
• W1973913077 hasConcept C86803240 @default.
• W1973913077 hasConcept C95444343 @default.
• W1973913077 hasConceptScore W1973913077C104317684 @default.
• W1973913077 hasConceptScore W1973913077C126322002 @default.
• W1973913077 hasConceptScore W1973913077C1491633281 @default.
• W1973913077 hasConceptScore W1973913077C150194340 @default.
• W1973913077 hasConceptScore W1973913077C16685009 @default.
• W1973913077 hasConceptScore W1973913077C171056886 @default.
• W1973913077 hasConceptScore W1973913077C179933525 @default.
• W1973913077 hasConceptScore W1973913077C196843134 @default.
• W1973913077 hasConceptScore W1973913077C203014093 @default.
• W1973913077 hasConceptScore W1973913077C2225953 @default.
• W1973913077 hasConceptScore W1973913077C2911091166 @default.
• W1973913077 hasConceptScore W1973913077C53227056 @default.
• W1973913077 hasConceptScore W1973913077C55493867 @default.
• W1973913077 hasConceptScore W1973913077C71924100 @default.
• W1973913077 hasConceptScore W1973913077C86803240 @default.
• W1973913077 hasConceptScore W1973913077C95444343 @default.
• W1973913077 hasIssue "2" @default.
• W1973913077 hasLocation W19739130771 @default.
• W1973913077 hasLocation W19739130772 @default.
• W1973913077 hasOpenAccess W1973913077 @default.
• W1973913077 hasPrimaryLocation W19739130771 @default.
• W1973913077 hasRelatedWork W1971044127 @default.
• W1973913077 hasRelatedWork W1971291175 @default.
• W1973913077 hasRelatedWork W2069540150 @default.
• W1973913077 hasRelatedWork W2083883875 @default.
• W1973913077 hasRelatedWork W2138758116 @default.
• W1973913077 hasRelatedWork W2148648143 @default.
• W1973913077 hasRelatedWork W2293716033 @default.
• W1973913077 hasRelatedWork W2353219288 @default.
• W1973913077 hasRelatedWork W2360131288 @default.
• W1973913077 hasRelatedWork W2897941300 @default.

• next