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- W1973913191 abstract "In 2013, the Global Initiative for Chronic Obstructive Lung Disease (GOLD) recommendations on COPD management and prevention were updated to include additional therapeutic options for patients based on severity using a combined assessment of symptoms, degree of airflow limitation and number of exacerbations. The objective of the present study was to quantify the prevalence and incidence of COPD in the UK and estimate disease severity by 2013 GOLD categories A/B (low risk) and C/D (high risk). Patients with a diagnosis of COPD aged ≥40 years were identified in the population-based Clinical Practice Research Datalink. Point prevalence was calculated on December 31,2013. Incidence was estimated using newly diagnosed patients between 2009-2013. Rates were standardised using 2011 UK population age and gender. % predicted FEV1, modified British Medical Research Council grade and exacerbations defined by Read codes and prescriptions were used to classify patients by GOLD categories. Patient characteristics were reported. 49,286 prevalent patients were diagnosed with COPD with mean age of 70 years; 51% were male. Median time since diagnosis was 5 years. Overall prevalence was 33.0 per 1,000 people (95% CI: 32.7-33.4). Of these, 66.4% were classified as GOLD A/B and 33.6% as GOLD C/D. 27,224 newly diagnosed patients were identified with mean age of 67 years at first diagnosis; 53% were male. Incidence was 2.2 per 1000 person-years (95% CI: 2.1-2.2). A third of COPD patients in the UK are considered high-risk according to the 2013 GOLD categories. Classification of patients is key to identifying appropriate treatment options to reduce symptoms and the frequency of COPD exacerbations." @default.
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- W1973913191 date "2014-11-01" @default.
- W1973913191 modified "2023-09-26" @default.
- W1973913191 title "Epidemiology and Severity of Chronic Obstructive Pulmonary Disease (COPD) in the United Kingdom (UK)" @default.
- W1973913191 doi "https://doi.org/10.1016/j.jval.2014.08.2019" @default.
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