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• W1973922846 endingPage "2698" @default.
• W1973922846 startingPage "2690" @default.
• W1973922846 abstract "Three racemic butanolides, majorenolide (1), majorynolide (2), and majoranolide (3), with 18 known compounds, including ten butanolides, i.e., litsenolide A2 (4), litsenolide B2 (5), litsenolide C1 (6), litsenolide C2 (7), hamabiwalactone A (8), hamabiwalactone B (9), litseakolide A (10), litseakolide B (11), isoobtusilactone (12), and obtusilactone (13); one lignan, i.e., (±)-syringaresinol (14), two flavans, i.e., (+)-catechin (15), and (−)-epicatechin (16), one coumarin, i.e., scopoletin (17), and four steroids, i.e., a mixture of β-sitosterol (18) and stigmasterol (19), and a mixture of β-sitosteryl-3-O-β-D-glucoside (20) and stigmasteryl-3-O-β-D-glucoside (21) were isolated from the root of Lindera akoensis. The structures of the isolates were elucidated by in-depth spectroscopic analysis. Compounds 1–3 were previously assigned a δ-lactone structure, which was then revised to a γ-lactone structure, based on 1D-NMR data. The cigar-HMBC technique was used to confirm the accuracy of the γ-lactone structure, and the zero [α] value of compounds 1–3 suggested that they were considerably racemized. Nine butanolides 1–3, 4–8, and 10 showed antimycobacterial activities against M. tuberculosis H37Rv, with MIC values of 15–50 μg/ml." @default.
• W1973922846 created "2016-06-24" @default.
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• W1973922846 date "2008-12-01" @default.
• W1973922846 modified "2023-10-17" @default.
• W1973922846 title "Antimycobacterial Butanolides from the Root of<i>Lindera akoensis</i>" @default.
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• W1973922846 doi "https://doi.org/10.1002/cbdv.200890223" @default.
• W1973922846 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19089827" @default.
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