FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1973931852> ?p ?o ?g. }

• W1973931852 endingPage "93" @default.
• W1973931852 startingPage "82" @default.
• W1973931852 abstract "This study assesses the effects of ATP and GTP on the kinetic properties of voltage-gated K+ currents in anatomically identified postganglionic sympathetic neurons innervating the submandibular gland and the masseter muscle in rats. Three types of K+ currents were isolated: the I(Af) steady-state inactivating at more hyperpolarized potentials, I(As) steady-state inactivating at less hyperpolarized potentials than I(Af) and the I(K) current independent of membrane potential. The kinetic properties of these currents were tested in neurons with ATP (4 mM) and GTP (0.5 mM) or without ATP and GTP in the intracellular solution. In glandular and muscular neurons in the absence of ATP and GTP in the intracellular solution, the current density of I(Af) was significantly larger (142 pA/pF and 166 pA/pF, respectively) comparing to cells with ATP and GTP (96 pA/pF and 100 pA/pF, respectively). The I(As) was larger only in glandular neurons (52 pA/pF vs. 37 pA/pF).Conversely, I(K) current density was smaller in glandular and muscular neurons without ATP and GTP (17 pA/pF and 31 pA/pF, respectively) comparing to cells with ATP and GTP (57 pA/pF and 58 pA/pF, respectively). In glandular (15.5 nA/ms vs. 6.9 nA/ms) and muscular (10.9 nA/ms vs. 7.5 nA/ms) neurons, the I(Af) activated faster in the absence of ATP and GTP. Half inactivation voltage of I(Af) in glandular (-110.0 mV vs. -119.7 mV) and muscular (-108.4 vs. -117.3 mV) neurons was shifted towards depolarization in the absence of ATP and GTP. We suggest that the kinetic properties of K+ currents in glandular and muscular sympathetic neurons change markedly in the absence of ATP and GTP in the cytoplasm. Effectiveness of steady-state inactivated currents (I(Af) and I(AS)) increased, while effectiveness of steady-state noninactivated currents decreased in the absence of ATP and GTP. The effects were more pronounced in glandular than in muscular neurons." @default.
• W1973931852 created "2016-06-24" @default.
• W1973931852 creator A5001815366 @default.
• W1973931852 creator A5007433002 @default.
• W1973931852 creator A5040717373 @default.
• W1973931852 creator A5074661187 @default.
• W1973931852 date "2006-01-01" @default.
• W1973931852 modified "2023-10-16" @default.
• W1973931852 title "Effects of ATP and GTP on voltage-gated K+ currents in glandular and muscular sympathetic neurons" @default.
• W1973931852 cites W1566654154 @default.
• W1973931852 cites W1575439657 @default.
• W1973931852 cites W1790243440 @default.
• W1973931852 cites W1856877643 @default.
• W1973931852 cites W1868485233 @default.
• W1973931852 cites W1926942776 @default.
• W1973931852 cites W1937739983 @default.
• W1973931852 cites W1972046379 @default.
• W1973931852 cites W1973911112 @default.
• W1973931852 cites W1979314412 @default.
• W1973931852 cites W1982395498 @default.
• W1973931852 cites W1990705309 @default.
• W1973931852 cites W1993401896 @default.
• W1973931852 cites W1997537641 @default.
• W1973931852 cites W1998628406 @default.
• W1973931852 cites W2009784490 @default.
• W1973931852 cites W2016335120 @default.
• W1973931852 cites W2017466638 @default.
• W1973931852 cites W2019531118 @default.
• W1973931852 cites W2024762752 @default.
• W1973931852 cites W2029345951 @default.
• W1973931852 cites W2030088978 @default.
• W1973931852 cites W2048255402 @default.
• W1973931852 cites W2051372861 @default.
• W1973931852 cites W2051979908 @default.
• W1973931852 cites W2054106801 @default.
• W1973931852 cites W2054402466 @default.
• W1973931852 cites W2059690890 @default.
• W1973931852 cites W2061832243 @default.
• W1973931852 cites W2061853004 @default.
• W1973931852 cites W2067686175 @default.
• W1973931852 cites W2068480472 @default.
• W1973931852 cites W2070212214 @default.
• W1973931852 cites W2077719913 @default.
• W1973931852 cites W2078903154 @default.
• W1973931852 cites W2080928002 @default.
• W1973931852 cites W2091434483 @default.
• W1973931852 cites W2093981058 @default.
• W1973931852 cites W2095946514 @default.
• W1973931852 cites W2099164489 @default.
• W1973931852 cites W2104794671 @default.
• W1973931852 cites W2113936437 @default.
• W1973931852 cites W2120364572 @default.
• W1973931852 cites W2121137104 @default.
• W1973931852 cites W2121562020 @default.
• W1973931852 cites W2126725618 @default.
• W1973931852 cites W2129706672 @default.
• W1973931852 cites W2139056451 @default.
• W1973931852 cites W2141584191 @default.
• W1973931852 cites W2145102240 @default.
• W1973931852 cites W2151489288 @default.
• W1973931852 cites W2154578917 @default.
• W1973931852 cites W2154606229 @default.
• W1973931852 cites W2157270289 @default.
• W1973931852 cites W2170527056 @default.
• W1973931852 cites W4298417379 @default.
• W1973931852 cites W2029267015 @default.
• W1973931852 doi "https://doi.org/10.1016/j.brainres.2005.10.077" @default.
• W1973931852 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16359644" @default.
• W1973931852 hasPublicationYear "2006" @default.
• W1973931852 type Work @default.
• W1973931852 sameAs 1973931852 @default.
• W1973931852 citedByCount "4" @default.
• W1973931852 crossrefType "journal-article" @default.
• W1973931852 hasAuthorship W1973931852A5001815366 @default.
• W1973931852 hasAuthorship W1973931852A5007433002 @default.
• W1973931852 hasAuthorship W1973931852A5040717373 @default.
• W1973931852 hasAuthorship W1973931852A5074661187 @default.
• W1973931852 hasConcept C118716 @default.
• W1973931852 hasConcept C12554922 @default.
• W1973931852 hasConcept C126322002 @default.
• W1973931852 hasConcept C134018914 @default.
• W1973931852 hasConcept C181199279 @default.
• W1973931852 hasConcept C181911157 @default.
• W1973931852 hasConcept C185592680 @default.
• W1973931852 hasConcept C55493867 @default.
• W1973931852 hasConcept C71924100 @default.
• W1973931852 hasConcept C79879829 @default.
• W1973931852 hasConcept C86803240 @default.
• W1973931852 hasConceptScore W1973931852C118716 @default.
• W1973931852 hasConceptScore W1973931852C12554922 @default.
• W1973931852 hasConceptScore W1973931852C126322002 @default.
• W1973931852 hasConceptScore W1973931852C134018914 @default.
• W1973931852 hasConceptScore W1973931852C181199279 @default.
• W1973931852 hasConceptScore W1973931852C181911157 @default.
• W1973931852 hasConceptScore W1973931852C185592680 @default.
• W1973931852 hasConceptScore W1973931852C55493867 @default.
• W1973931852 hasConceptScore W1973931852C71924100 @default.
• W1973931852 hasConceptScore W1973931852C79879829 @default.

• next