FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1973943487> ?p ?o ?g. }

• W1973943487 endingPage "91" @default.
• W1973943487 startingPage "571" @default.
• W1973943487 abstract "The distribution and cellular localization of connexin32 (Cx32) in the brain and spinal cord of the mouse and rat was investigated by light microscope (LM) and electron microscope (EM) immunohistochemistry by using several different antibodies against Cx32. By double immunofluorescence staining for Cx32 and either the oligodendrocyte markers cyclic nucleotide phosphodiesterase (CNPase) or Rip, Cx32 was consistently found in oligodendrocyte cell bodies and proximal processes. Cx32 immunoreactivity was also clearly visualized along CNPase- and Rip-positive myelinated fibers. Both immunopositive cells and fibers were heterogeneously distributed and were often more intensely labeled when dispersed in or associated with regions of gray matter than when concentrated in major white matter tracts. Labeling of myelin sheaths along fibers was restricted to subpopulations of myelinated axons. In the cerebellar cortex, for example, it was selectively localized to sheaths around Purkinje cell axons. Punctate staining, distinct from that corresponding to cells or fibers, was evident in the olfactory bulb and hippocampus. By EM, oligodendrocytes exhibited cytoplasmic labeling associated with rough endoplasmic reticulum and Golgi apparatus. Their processes were intermittently stained, most intensely when surrounding myelinated fibers and occasionally in paranodal loops. Cx32-immunoreactive gap junctions with symmetric labeling (staining on both junctional membranes) were observed between oligodendrocytic somata and processes as well as between presumptive oligodendrocytic processes. Unidentifiable elements forming asymmetrically labeled gap junctions (staining only one side of junctional membranes) were less frequently encountered. Western blot analysis confirmed anti-Cx32 antibody detection of Cx32 in whole brain homogenates and an enrichment of the protein in isolated myelin fractions. These results are consistent with earlier ultrastructural studies showing the occurrence of inter-oligodendrocytic gap junctions, but indicate that these may be more prevalent than previously thought. Furthermore, the results suggest a specialized role of gap junctions composed of Cx32 along myelinated fibers belonging to subpopulations of neurons." @default.
• W1973943487 created "2016-06-24" @default.
• W1973943487 creator A5018313164 @default.
• W1973943487 creator A5061726638 @default.
• W1973943487 creator A5069620849 @default.
• W1973943487 date "1997-03-24" @default.
• W1973943487 modified "2023-10-16" @default.
• W1973943487 title "Connexin32 in oligodendrocytes and association with myelinated fibers in mouse and rat brain." @default.
• W1973943487 cites W1526371099 @default.
• W1973943487 cites W1563929437 @default.
• W1973943487 cites W1578786288 @default.
• W1973943487 cites W1592916130 @default.
• W1973943487 cites W1635997158 @default.
• W1973943487 cites W1658489072 @default.
• W1973943487 cites W1682302400 @default.
• W1973943487 cites W1864765563 @default.
• W1973943487 cites W1964405560 @default.
• W1973943487 cites W1968577463 @default.
• W1973943487 cites W1971184608 @default.
• W1973943487 cites W1978218920 @default.
• W1973943487 cites W1984345680 @default.
• W1973943487 cites W1985051923 @default.
• W1973943487 cites W1988316236 @default.
• W1973943487 cites W1989105491 @default.
• W1973943487 cites W1989657414 @default.
• W1973943487 cites W1991003145 @default.
• W1973943487 cites W1993191579 @default.
• W1973943487 cites W1994463799 @default.
• W1973943487 cites W1995192089 @default.
• W1973943487 cites W1995233250 @default.
• W1973943487 cites W2000426620 @default.
• W1973943487 cites W2000609872 @default.
• W1973943487 cites W2004082340 @default.
• W1973943487 cites W2012654459 @default.
• W1973943487 cites W2019329906 @default.
• W1973943487 cites W2021752645 @default.
• W1973943487 cites W2028120904 @default.
• W1973943487 cites W2030743632 @default.
• W1973943487 cites W2031785864 @default.
• W1973943487 cites W2032171471 @default.
• W1973943487 cites W2032214543 @default.
• W1973943487 cites W2033835887 @default.
• W1973943487 cites W2038939314 @default.
• W1973943487 cites W2039390627 @default.
• W1973943487 cites W2041355230 @default.
• W1973943487 cites W2047841570 @default.
• W1973943487 cites W2051304964 @default.
• W1973943487 cites W2054245229 @default.
• W1973943487 cites W2054361548 @default.
• W1973943487 cites W2056277059 @default.
• W1973943487 cites W2056482899 @default.
• W1973943487 cites W2056888320 @default.
• W1973943487 cites W2058260122 @default.
• W1973943487 cites W2060693006 @default.
• W1973943487 cites W2061101618 @default.
• W1973943487 cites W2064258187 @default.
• W1973943487 cites W2071307343 @default.
• W1973943487 cites W2076203858 @default.
• W1973943487 cites W2078770943 @default.
• W1973943487 cites W2080202616 @default.
• W1973943487 cites W2081669905 @default.
• W1973943487 cites W2085325012 @default.
• W1973943487 cites W2087188546 @default.
• W1973943487 cites W2087667366 @default.
• W1973943487 cites W2087849583 @default.
• W1973943487 cites W2090971379 @default.
• W1973943487 cites W2094412950 @default.
• W1973943487 cites W2095272418 @default.
• W1973943487 cites W2100260123 @default.
• W1973943487 cites W2113755529 @default.
• W1973943487 cites W2116763991 @default.
• W1973943487 cites W2119346041 @default.
• W1973943487 cites W2126154316 @default.
• W1973943487 cites W2144785163 @default.
• W1973943487 cites W2155062237 @default.
• W1973943487 cites W2161278067 @default.
• W1973943487 cites W2164557885 @default.
• W1973943487 cites W2496136908 @default.
• W1973943487 cites W4237956819 @default.
• W1973943487 cites W4246496924 @default.
• W1973943487 cites W2036598786 @default.
• W1973943487 cites W2123473423 @default.
• W1973943487 doi "https://doi.org/10.1002/(sici)1096-9861(19970324)379:4<571::aid-cne8>3.0.co;2-" @default.
• W1973943487 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9067844" @default.
• W1973943487 hasPublicationYear "1997" @default.
• W1973943487 type Work @default.
• W1973943487 sameAs 1973943487 @default.
• W1973943487 citedByCount "97" @default.
• W1973943487 countsByYear W19739434872012 @default.
• W1973943487 countsByYear W19739434872013 @default.
• W1973943487 countsByYear W19739434872017 @default.
• W1973943487 countsByYear W19739434872022 @default.
• W1973943487 crossrefType "journal-article" @default.
• W1973943487 hasAuthorship W1973943487A5018313164 @default.
• W1973943487 hasAuthorship W1973943487A5061726638 @default.
• W1973943487 hasAuthorship W1973943487A5069620849 @default.
• W1973943487 hasConcept C119062480 @default.
• W1973943487 hasConcept C126838900 @default.

• next