FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1973947673> ?p ?o ?g. }

• W1973947673 endingPage "7071" @default.
• W1973947673 startingPage "7069" @default.
• W1973947673 abstract "Early metazoan development is programmed by maternal mRNAs inherited by the egg at the time of fertilization. These mRNAs are not translated en masse at any one time or at any one place, but instead their expression is regulated both temporally and spatially. Recent evidence has shown that one maternal mRNA, cyclin B1, is concentrated on mitotic spindles in the early Xenopus embryo, where its translation is controlled by CPEB (cytoplasmic polyadenylation element binding protein), a sequence-specific RNA binding protein. Disruption of the spindle-associated translation of this mRNA results in a morphologically abnormal mitotic apparatus and inhibited cell division. Mammalian neurons, particularly in the synapto-dendritic compartment, also contain localized mRNAs such as that encoding alpha-CaMKII. Here, synaptic activation drives local translation, an event that is involved in synaptic plasticity and possibly long-term memory storage. Synaptic translation of alpha-CaMKII mRNA also appears to be controlled by CPEB, which is enriched in the postsynaptic density. Therefore, CPEB-controlled local translation may influence such seemingly disparate processes as the cell cycle and synaptic plasticity." @default.
• W1973947673 created "2016-06-24" @default.
• W1973947673 creator A5042061460 @default.
• W1973947673 date "2001-06-19" @default.
• W1973947673 modified "2023-09-30" @default.
• W1973947673 title "Think globally, translate locally: What mitotic spindles and neuronal synapses have in common" @default.
• W1973947673 cites W1591026223 @default.
• W1973947673 cites W1937698251 @default.
• W1973947673 cites W1979496428 @default.
• W1973947673 cites W1986699200 @default.
• W1973947673 cites W1990118065 @default.
• W1973947673 cites W2007863157 @default.
• W1973947673 cites W2009629503 @default.
• W1973947673 cites W2026998769 @default.
• W1973947673 cites W2035298842 @default.
• W1973947673 cites W2040418544 @default.
• W1973947673 cites W2044273755 @default.
• W1973947673 cites W2048146797 @default.
• W1973947673 cites W2054975255 @default.
• W1973947673 cites W2057983666 @default.
• W1973947673 cites W2058053468 @default.
• W1973947673 cites W2059010387 @default.
• W1973947673 cites W2069930342 @default.
• W1973947673 cites W2080252952 @default.
• W1973947673 cites W2082079131 @default.
• W1973947673 cites W2089784855 @default.
• W1973947673 cites W2092590107 @default.
• W1973947673 cites W2097734332 @default.
• W1973947673 cites W2109851824 @default.
• W1973947673 cites W2111760870 @default.
• W1973947673 cites W2136667549 @default.
• W1973947673 cites W2137433892 @default.
• W1973947673 cites W2145913988 @default.
• W1973947673 cites W2146686648 @default.
• W1973947673 cites W2157497892 @default.
• W1973947673 doi "https://doi.org/10.1073/pnas.111146498" @default.
• W1973947673 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/34624" @default.
• W1973947673 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11416189" @default.
• W1973947673 hasPublicationYear "2001" @default.
• W1973947673 type Work @default.
• W1973947673 sameAs 1973947673 @default.
• W1973947673 citedByCount "76" @default.
• W1973947673 countsByYear W19739476732012 @default.
• W1973947673 countsByYear W19739476732013 @default.
• W1973947673 countsByYear W19739476732014 @default.
• W1973947673 countsByYear W19739476732015 @default.
• W1973947673 countsByYear W19739476732016 @default.
• W1973947673 countsByYear W19739476732017 @default.
• W1973947673 countsByYear W19739476732018 @default.
• W1973947673 countsByYear W19739476732019 @default.
• W1973947673 countsByYear W19739476732020 @default.
• W1973947673 countsByYear W19739476732021 @default.
• W1973947673 countsByYear W19739476732022 @default.
• W1973947673 countsByYear W19739476732023 @default.
• W1973947673 crossrefType "journal-article" @default.
• W1973947673 hasAuthorship W1973947673A5042061460 @default.
• W1973947673 hasBestOaLocation W19739476731 @default.
• W1973947673 hasConcept C104317684 @default.
• W1973947673 hasConcept C105580179 @default.
• W1973947673 hasConcept C142575336 @default.
• W1973947673 hasConcept C149364088 @default.
• W1973947673 hasConcept C169760540 @default.
• W1973947673 hasConcept C170493617 @default.
• W1973947673 hasConcept C2779535977 @default.
• W1973947673 hasConcept C41282012 @default.
• W1973947673 hasConcept C54355233 @default.
• W1973947673 hasConcept C86803240 @default.
• W1973947673 hasConcept C93304396 @default.
• W1973947673 hasConcept C95444343 @default.
• W1973947673 hasConcept C98229152 @default.
• W1973947673 hasConceptScore W1973947673C104317684 @default.
• W1973947673 hasConceptScore W1973947673C105580179 @default.
• W1973947673 hasConceptScore W1973947673C142575336 @default.
• W1973947673 hasConceptScore W1973947673C149364088 @default.
• W1973947673 hasConceptScore W1973947673C169760540 @default.
• W1973947673 hasConceptScore W1973947673C170493617 @default.
• W1973947673 hasConceptScore W1973947673C2779535977 @default.
• W1973947673 hasConceptScore W1973947673C41282012 @default.
• W1973947673 hasConceptScore W1973947673C54355233 @default.
• W1973947673 hasConceptScore W1973947673C86803240 @default.
• W1973947673 hasConceptScore W1973947673C93304396 @default.
• W1973947673 hasConceptScore W1973947673C95444343 @default.
• W1973947673 hasConceptScore W1973947673C98229152 @default.
• W1973947673 hasIssue "13" @default.
• W1973947673 hasLocation W19739476731 @default.
• W1973947673 hasLocation W19739476732 @default.
• W1973947673 hasLocation W19739476733 @default.
• W1973947673 hasLocation W19739476734 @default.
• W1973947673 hasOpenAccess W1973947673 @default.
• W1973947673 hasPrimaryLocation W19739476731 @default.
• W1973947673 hasRelatedWork W1983255013 @default.
• W1973947673 hasRelatedWork W1992868294 @default.
• W1973947673 hasRelatedWork W2009982711 @default.
• W1973947673 hasRelatedWork W2023978881 @default.
• W1973947673 hasRelatedWork W2041712585 @default.
• W1973947673 hasRelatedWork W2051870959 @default.
• W1973947673 hasRelatedWork W2121629831 @default.
• W1973947673 hasRelatedWork W2473292382 @default.

• next