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• W1974035734 abstract "Resolution of three commonly used beta-blockers, (+/-)-atenolol, (+/-)-metoprolol and (+/-)-propranolol, into their enantiomers has been achieved using normal-phase TLC on silica gel plates impregnated with L-aspartic acid as the chiral selector. Different combinations of acetonitrile-methanol-water as mobile phase were found to be successful in resolving the enantiomers. The spots were detected with iodine and the detection limits were found to be 0.26 microg for atenolol and 0.23 microg for each of metoprolol and propranolol as racemate." @default.
• W1974035734 created "2016-06-24" @default.
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• W1974035734 date "2003-04-11" @default.
• W1974035734 modified "2023-09-26" @default.
• W1974035734 title "Direct enantiomeric resolution of (±)-atenolol, (±)-metoprolol, and (±)-propranolol by impregnated TLC using<scp>L</scp>-aspartic acid as chiral selector" @default.
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• W1974035734 doi "https://doi.org/10.1002/bmc.216" @default.
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