Matches in SemOpenAlex for { <https://semopenalex.org/work/W1974083313> ?p ?o ?g. }
- W1974083313 endingPage "677" @default.
- W1974083313 startingPage "672" @default.
- W1974083313 abstract "The macrophage resistance gene NRAMP1 regulates priming/activation of macrophages for enhanced TNF alpha, IL 1 beta, and MHC class II expression. Since all of these functions are of potential importance in the induction or maintenance or both of autoimmune disease, samples from the Arthritis and Rheumatism Council's repository of multicase rheumatoid arthritis families were typed for a dinucleotide repeat in the NRAMP1 promoter region and four other 2q34 (TNP1) or 2q35 (IL8R, VIL1, DES) marker genes. Identity by descent (IBD) sib pair analysis using a three locus haplotype NRAMP1-IL8RB-VIL1, or NRAMP1 alone, provided preliminary evidence (maximum lod score = 1.01, p = 0.024) for a gene in this region contributing to suceptibility to rheumatoid arthritis. Candidacy for NRAMP1 as the disease susceptibility gene was supported by a significant bias (p = 0.048) towards transmission of the NRAMP1 promoter region allele 3 in affected offspring." @default.
- W1974083313 created "2016-06-24" @default.
- W1974083313 creator A5026993865 @default.
- W1974083313 creator A5044471684 @default.
- W1974083313 creator A5048555654 @default.
- W1974083313 creator A5051359259 @default.
- W1974083313 creator A5074203084 @default.
- W1974083313 creator A5083319462 @default.
- W1974083313 creator A5084765206 @default.
- W1974083313 date "1996-08-01" @default.
- W1974083313 modified "2023-10-14" @default.
- W1974083313 title "Linkage of rheumatoid arthritis to the candidate gene NRAMP1 on 2q35." @default.
- W1974083313 cites W136910319 @default.
- W1974083313 cites W1483702399 @default.
- W1974083313 cites W1483737778 @default.
- W1974083313 cites W1499143852 @default.
- W1974083313 cites W1515471646 @default.
- W1974083313 cites W1518689009 @default.
- W1974083313 cites W1543868019 @default.
- W1974083313 cites W1641197739 @default.
- W1974083313 cites W1733541714 @default.
- W1974083313 cites W1916899229 @default.
- W1974083313 cites W1976741643 @default.
- W1974083313 cites W1983618700 @default.
- W1974083313 cites W1984493755 @default.
- W1974083313 cites W1989632139 @default.
- W1974083313 cites W1990226212 @default.
- W1974083313 cites W1996152259 @default.
- W1974083313 cites W2008350626 @default.
- W1974083313 cites W2010148594 @default.
- W1974083313 cites W2016708020 @default.
- W1974083313 cites W2036260827 @default.
- W1974083313 cites W2041583495 @default.
- W1974083313 cites W2063273369 @default.
- W1974083313 cites W2063504630 @default.
- W1974083313 cites W2063940041 @default.
- W1974083313 cites W2065665571 @default.
- W1974083313 cites W2073446457 @default.
- W1974083313 cites W2078667657 @default.
- W1974083313 cites W2082959093 @default.
- W1974083313 cites W2084001516 @default.
- W1974083313 cites W2086419846 @default.
- W1974083313 cites W2086708191 @default.
- W1974083313 cites W2086755979 @default.
- W1974083313 cites W2105672618 @default.
- W1974083313 cites W2118265734 @default.
- W1974083313 cites W2143988830 @default.
- W1974083313 cites W2160498502 @default.
- W1974083313 cites W2170008072 @default.
- W1974083313 cites W2180743237 @default.
- W1974083313 cites W2419218621 @default.
- W1974083313 cites W263234597 @default.
- W1974083313 cites W48750798 @default.
- W1974083313 doi "https://doi.org/10.1136/jmg.33.8.672" @default.
- W1974083313 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1050702" @default.
- W1974083313 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8863160" @default.
- W1974083313 hasPublicationYear "1996" @default.
- W1974083313 type Work @default.
- W1974083313 sameAs 1974083313 @default.
- W1974083313 citedByCount "79" @default.
- W1974083313 countsByYear W19740833132013 @default.
- W1974083313 countsByYear W19740833132014 @default.
- W1974083313 countsByYear W19740833132015 @default.
- W1974083313 countsByYear W19740833132016 @default.
- W1974083313 countsByYear W19740833132017 @default.
- W1974083313 countsByYear W19740833132018 @default.
- W1974083313 countsByYear W19740833132019 @default.
- W1974083313 countsByYear W19740833132020 @default.
- W1974083313 crossrefType "journal-article" @default.
- W1974083313 hasAuthorship W1974083313A5026993865 @default.
- W1974083313 hasAuthorship W1974083313A5044471684 @default.
- W1974083313 hasAuthorship W1974083313A5048555654 @default.
- W1974083313 hasAuthorship W1974083313A5051359259 @default.
- W1974083313 hasAuthorship W1974083313A5074203084 @default.
- W1974083313 hasAuthorship W1974083313A5083319462 @default.
- W1974083313 hasAuthorship W1974083313A5084765206 @default.
- W1974083313 hasBestOaLocation W19740833131 @default.
- W1974083313 hasConcept C104317684 @default.
- W1974083313 hasConcept C142870003 @default.
- W1974083313 hasConcept C180754005 @default.
- W1974083313 hasConcept C197754878 @default.
- W1974083313 hasConcept C203014093 @default.
- W1974083313 hasConcept C2777077863 @default.
- W1974083313 hasConcept C2777575956 @default.
- W1974083313 hasConcept C54355233 @default.
- W1974083313 hasConcept C69991583 @default.
- W1974083313 hasConcept C71924100 @default.
- W1974083313 hasConcept C84597430 @default.
- W1974083313 hasConcept C86803240 @default.
- W1974083313 hasConceptScore W1974083313C104317684 @default.
- W1974083313 hasConceptScore W1974083313C142870003 @default.
- W1974083313 hasConceptScore W1974083313C180754005 @default.
- W1974083313 hasConceptScore W1974083313C197754878 @default.
- W1974083313 hasConceptScore W1974083313C203014093 @default.
- W1974083313 hasConceptScore W1974083313C2777077863 @default.
- W1974083313 hasConceptScore W1974083313C2777575956 @default.
- W1974083313 hasConceptScore W1974083313C54355233 @default.
- W1974083313 hasConceptScore W1974083313C69991583 @default.