Matches in SemOpenAlex for { <https://semopenalex.org/work/W1974135197> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W1974135197 endingPage "187" @default.
- W1974135197 startingPage "175" @default.
- W1974135197 abstract "1. Two CYP1A proteins, designated HAP 1 and HAP 2, were isolated from the liver of the beta-naphthoflavone (BNF)-treated rainbow trout. The proteins were initially resolved by chromatography on a DEAE sepharose column and were further purified by hydroxyl-apatite chromatography. 2. Both HAP 1 and HAP 2 proteins exhibited high 7-ethoxyresorufin, methoxy-resorufin and phenacetin O-dealkylase activities and were good catalysts for the oxidation of 7,12-dimethylbenz[a]anthracene (DMBA). No qualitative difference was observed between the two proteins in their ability to catalyse the formation of the individual metabolites of DMBA. 3. The two purified proteins showed identical amino acid sequence for the first 13 amino acids. However, the 14th amino acid was valine for HAP 1 protein and alanine for HAP 2 protein. 4. Alignment of the amino acid sequences showed that HAP 1 protein was identical to the deduced protein of the previously reported trout CYP1A2 (renamed CYP1A1) gene for the first 24 amino acids at the N-terminal region. HAP 2 protein corresponded to the deduced protein sequence of CYP1A3 gene for the first 14 amino acids. However, unlike the deduced sequences of CYP1A1 and 1A3 the N-terminal methionine was absent in the purified proteins. 5. We conclude that HAP 1 and HAP 2 are the products of the CYP1A1 and CYP1A3 genes respectively, and are found in the liver of the BNF-treated rainbow trout." @default.
- W1974135197 created "2016-06-24" @default.
- W1974135197 creator A5012008989 @default.
- W1974135197 creator A5014474421 @default.
- W1974135197 creator A5036134484 @default.
- W1974135197 creator A5078344835 @default.
- W1974135197 date "1997-01-01" @default.
- W1974135197 modified "2023-10-09" @default.
- W1974135197 title "<i>β</i>-Naphthoflavone induced CYP1A1 and 1A3 proteins in the liver of rainbow trout (<i>Oncorhynchus mykiss</i>)" @default.
- W1974135197 cites W1563870362 @default.
- W1974135197 cites W1775749144 @default.
- W1974135197 cites W1932052686 @default.
- W1974135197 cites W1951469402 @default.
- W1974135197 cites W1964198497 @default.
- W1974135197 cites W1984490307 @default.
- W1974135197 cites W1988617504 @default.
- W1974135197 cites W1997048544 @default.
- W1974135197 cites W2023341739 @default.
- W1974135197 cites W2069079331 @default.
- W1974135197 cites W2077945512 @default.
- W1974135197 cites W2079807348 @default.
- W1974135197 cites W2095173308 @default.
- W1974135197 cites W2100837269 @default.
- W1974135197 cites W2111817213 @default.
- W1974135197 cites W2132927623 @default.
- W1974135197 cites W2164962428 @default.
- W1974135197 cites W246383350 @default.
- W1974135197 doi "https://doi.org/10.1080/004982597240677" @default.
- W1974135197 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9058531" @default.
- W1974135197 hasPublicationYear "1997" @default.
- W1974135197 type Work @default.
- W1974135197 sameAs 1974135197 @default.
- W1974135197 citedByCount "36" @default.
- W1974135197 countsByYear W19741351972012 @default.
- W1974135197 countsByYear W19741351972013 @default.
- W1974135197 countsByYear W19741351972015 @default.
- W1974135197 countsByYear W19741351972016 @default.
- W1974135197 countsByYear W19741351972017 @default.
- W1974135197 countsByYear W19741351972018 @default.
- W1974135197 crossrefType "journal-article" @default.
- W1974135197 hasAuthorship W1974135197A5012008989 @default.
- W1974135197 hasAuthorship W1974135197A5014474421 @default.
- W1974135197 hasAuthorship W1974135197A5036134484 @default.
- W1974135197 hasAuthorship W1974135197A5078344835 @default.
- W1974135197 hasConcept C104317684 @default.
- W1974135197 hasConcept C167625842 @default.
- W1974135197 hasConcept C179247698 @default.
- W1974135197 hasConcept C181199279 @default.
- W1974135197 hasConcept C185592680 @default.
- W1974135197 hasConcept C2777573094 @default.
- W1974135197 hasConcept C2779856020 @default.
- W1974135197 hasConcept C2780912031 @default.
- W1974135197 hasConcept C2909208804 @default.
- W1974135197 hasConcept C2994167347 @default.
- W1974135197 hasConcept C505870484 @default.
- W1974135197 hasConcept C515207424 @default.
- W1974135197 hasConcept C55493867 @default.
- W1974135197 hasConcept C86803240 @default.
- W1974135197 hasConceptScore W1974135197C104317684 @default.
- W1974135197 hasConceptScore W1974135197C167625842 @default.
- W1974135197 hasConceptScore W1974135197C179247698 @default.
- W1974135197 hasConceptScore W1974135197C181199279 @default.
- W1974135197 hasConceptScore W1974135197C185592680 @default.
- W1974135197 hasConceptScore W1974135197C2777573094 @default.
- W1974135197 hasConceptScore W1974135197C2779856020 @default.
- W1974135197 hasConceptScore W1974135197C2780912031 @default.
- W1974135197 hasConceptScore W1974135197C2909208804 @default.
- W1974135197 hasConceptScore W1974135197C2994167347 @default.
- W1974135197 hasConceptScore W1974135197C505870484 @default.
- W1974135197 hasConceptScore W1974135197C515207424 @default.
- W1974135197 hasConceptScore W1974135197C55493867 @default.
- W1974135197 hasConceptScore W1974135197C86803240 @default.
- W1974135197 hasIssue "2" @default.
- W1974135197 hasLocation W19741351971 @default.
- W1974135197 hasLocation W19741351972 @default.
- W1974135197 hasOpenAccess W1974135197 @default.
- W1974135197 hasPrimaryLocation W19741351971 @default.
- W1974135197 hasRelatedWork W1534081916 @default.
- W1974135197 hasRelatedWork W1543922870 @default.
- W1974135197 hasRelatedWork W1969676960 @default.
- W1974135197 hasRelatedWork W1994623271 @default.
- W1974135197 hasRelatedWork W2011517960 @default.
- W1974135197 hasRelatedWork W2016647084 @default.
- W1974135197 hasRelatedWork W2052955587 @default.
- W1974135197 hasRelatedWork W2072190170 @default.
- W1974135197 hasRelatedWork W2165455688 @default.
- W1974135197 hasRelatedWork W2395117863 @default.
- W1974135197 hasVolume "27" @default.
- W1974135197 isParatext "false" @default.
- W1974135197 isRetracted "false" @default.
- W1974135197 magId "1974135197" @default.
- W1974135197 workType "article" @default.