FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1974161540> ?p ?o ?g. }

• W1974161540 endingPage "160" @default.
• W1974161540 startingPage "155" @default.
• W1974161540 abstract "<i>Background:</i> The results of the very few histochemical studies that have been performed so far on the lectin-binding profile of normal human epidermis are mostly controversial; thus, the carbohydrate residue composition of the cell surface in the latter still remains in dispute and the possible alterations in the epidermal lectin-binding profile are unknown. <i>Objective:</i> To investigate the influence of age on the carbohydrate residue composition of the cell surface in unexposed normal human epidermis by means of lectin histochemistry. <i>Methods:</i> Biopsy specimens obtained from the sun-protected (unexposed) buttock skin, divided into 5 age groups of 18 subjects each, were fixed in buffered formalin (10%) and embedded in paraffin. 4-µm sections were processed for histochemistry using a panel of six biotinylated lectins. <i>Results:</i> In the unexposed normal human epidermis the concentration and distribution of cell surface β-<i>D</i>-galactose, <i>D</i>-galactose-β-(1,3 N-acetylo-<i>D</i>-galactosamine), β(1,4 <i>D</i>-N-acetylo-<i>D</i>-glucosamine) and α-<i>D</i>-N-acetylo-<i>D</i>-galactosamine were almost identical in all age groups, whereas those of α-<i>D</i>-mannose, α-<i>D</i>-glucose and α-<i>L</i>-fucose revealed significant age-related differences. <i>Conclusion:</i> These findings may be due to an age-related decline in synthesis and/or transport of monosaccharides from the cytoplasm to the surface of epidermal cells. Thus, the corresponding lectins concanavalin A and <i>Ulex europaeus</i> agglutinin-I can only be used in comparative histochemical studies of the carbohydrate residue composition of the cell surface in the normal and pathological epidermis of individuals of the same age, whereas <i>Ricinus communis </i>agglutinin-I, peanut agglutinin, wheat germ agglutinin and <i>Dolichos biflorus</i> agglutinin, whose binding to carbohydrates is not affected by aging can be used in histochemical studies of carbohydrate residue composition of the cell surface in the normal and pathological epidermis in human subjects of any age." @default.
• W1974161540 created "2016-06-24" @default.
• W1974161540 creator A5006636659 @default.
• W1974161540 creator A5007949204 @default.
• W1974161540 creator A5016298902 @default.
• W1974161540 creator A5061695743 @default.
• W1974161540 creator A5074497379 @default.
• W1974161540 creator A5078167342 @default.
• W1974161540 date "2005-01-01" @default.
• W1974161540 modified "2023-09-27" @default.
• W1974161540 title "Age-Related Alterations in the Carbohydrate Residue Composition of the Cell Surface in the Unexposed Normal Human Epidermis" @default.
• W1974161540 cites W1981370590 @default.
• W1974161540 cites W1984509045 @default.
• W1974161540 cites W1986012234 @default.
• W1974161540 cites W2001253603 @default.
• W1974161540 cites W2007080026 @default.
• W1974161540 cites W2008562048 @default.
• W1974161540 cites W2008634606 @default.
• W1974161540 cites W2012875514 @default.
• W1974161540 cites W2043812306 @default.
• W1974161540 cites W2081605478 @default.
• W1974161540 cites W2089637241 @default.
• W1974161540 cites W2094216653 @default.
• W1974161540 cites W2315300044 @default.
• W1974161540 cites W4211202129 @default.
• W1974161540 doi "https://doi.org/10.1159/000083986" @default.
• W1974161540 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15832040" @default.
• W1974161540 hasPublicationYear "2005" @default.
• W1974161540 type Work @default.
• W1974161540 sameAs 1974161540 @default.
• W1974161540 citedByCount "5" @default.
• W1974161540 countsByYear W19741615402012 @default.
• W1974161540 countsByYear W19741615402015 @default.
• W1974161540 crossrefType "journal-article" @default.
• W1974161540 hasAuthorship W1974161540A5006636659 @default.
• W1974161540 hasAuthorship W1974161540A5007949204 @default.
• W1974161540 hasAuthorship W1974161540A5016298902 @default.
• W1974161540 hasAuthorship W1974161540A5061695743 @default.
• W1974161540 hasAuthorship W1974161540A5074497379 @default.
• W1974161540 hasAuthorship W1974161540A5078167342 @default.
• W1974161540 hasConcept C105702510 @default.
• W1974161540 hasConcept C153911025 @default.
• W1974161540 hasConcept C185592680 @default.
• W1974161540 hasConcept C203014093 @default.
• W1974161540 hasConcept C204232928 @default.
• W1974161540 hasConcept C2776458125 @default.
• W1974161540 hasConcept C2778173381 @default.
• W1974161540 hasConcept C2778977261 @default.
• W1974161540 hasConcept C2781467277 @default.
• W1974161540 hasConcept C55493867 @default.
• W1974161540 hasConcept C86803240 @default.
• W1974161540 hasConceptScore W1974161540C105702510 @default.
• W1974161540 hasConceptScore W1974161540C153911025 @default.
• W1974161540 hasConceptScore W1974161540C185592680 @default.
• W1974161540 hasConceptScore W1974161540C203014093 @default.
• W1974161540 hasConceptScore W1974161540C204232928 @default.
• W1974161540 hasConceptScore W1974161540C2776458125 @default.
• W1974161540 hasConceptScore W1974161540C2778173381 @default.
• W1974161540 hasConceptScore W1974161540C2778977261 @default.
• W1974161540 hasConceptScore W1974161540C2781467277 @default.
• W1974161540 hasConceptScore W1974161540C55493867 @default.
• W1974161540 hasConceptScore W1974161540C86803240 @default.
• W1974161540 hasIssue "3" @default.
• W1974161540 hasLocation W19741615401 @default.
• W1974161540 hasLocation W19741615402 @default.
• W1974161540 hasOpenAccess W1974161540 @default.
• W1974161540 hasPrimaryLocation W19741615401 @default.
• W1974161540 hasRelatedWork W1963548040 @default.
• W1974161540 hasRelatedWork W1965603131 @default.
• W1974161540 hasRelatedWork W1989755376 @default.
• W1974161540 hasRelatedWork W1998730445 @default.
• W1974161540 hasRelatedWork W2007084386 @default.
• W1974161540 hasRelatedWork W2009701344 @default.
• W1974161540 hasRelatedWork W2021972333 @default.
• W1974161540 hasRelatedWork W2173766320 @default.
• W1974161540 hasRelatedWork W2315008805 @default.
• W1974161540 hasRelatedWork W2323583704 @default.
• W1974161540 hasVolume "51" @default.
• W1974161540 isParatext "false" @default.
• W1974161540 isRetracted "false" @default.
• W1974161540 magId "1974161540" @default.
• W1974161540 workType "article" @default.