Matches in SemOpenAlex for { <https://semopenalex.org/work/W1974387743> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W1974387743 endingPage "191" @default.
- W1974387743 startingPage "179" @default.
- W1974387743 abstract "A Review on Toxicity of 2‐Bromopropane : Mainly on its Reproductive Toxicity: Yasuhiro T akeuchi , et al. Department of Hygiene, Nagoya University School of Medicine —2‐Bromopropane has been used mostly as an intermediate for medicines, pesticides and other chemicals in closed systems. Recently it has come to be used as an alternative solvent in open systems instead of ozone layer depleting chlorofluorocarbons. An outbreak of reproductive and hematopoietic disorders occurred in workers exposed to solvents containing 2‐bromopropane in a Korean factory in 1995. After that some animal experiments revealed that 2‐bromopropane has a severe toxic effect on the female and male reproductive organs and hematopoietic organs. We reviewed the toxicity of 2‐bromopropane based on the recent data obtained in epidemiological surveys and animal experiments. Toxicities of structurally related bromopropanes were compared with that of 2‐bromopropane and its risk assessment was discussed. The conclusions are as follows: 1. 2‐Bromopropane has a specific reproductive and hematopoietic toxicity in both sexes in humans and experimental animals. 2. It could impair the testes, especially spermatogonia in males. 3. It could impair the ovarian function, resulting in a disturbed estrous cycle and loss of oocytes in females. 4. It could impair the bone marrow, resulting in pancytopenia. 5. It has a weak potent mutagenicity in bacterial mutation assays. 6. A risk assessment suggests that around 0.3‐10 ppm might be recommended as an occupational exposure limit for 2‐bromopropane." @default.
- W1974387743 created "2016-06-24" @default.
- W1974387743 creator A5046784299 @default.
- W1974387743 creator A5059572624 @default.
- W1974387743 creator A5076994948 @default.
- W1974387743 date "1997-07-01" @default.
- W1974387743 modified "2023-09-26" @default.
- W1974387743 title "A Review on Toxicity of 2‐Bromopropane: Mainly on its Reproductive Toxicity" @default.
- W1974387743 cites W1967196821 @default.
- W1974387743 cites W1973384775 @default.
- W1974387743 cites W1991182942 @default.
- W1974387743 cites W1991603755 @default.
- W1974387743 cites W1992862733 @default.
- W1974387743 cites W1999111550 @default.
- W1974387743 cites W2007364313 @default.
- W1974387743 cites W2019872943 @default.
- W1974387743 cites W2022671844 @default.
- W1974387743 cites W2023861166 @default.
- W1974387743 cites W2025933799 @default.
- W1974387743 cites W2037322841 @default.
- W1974387743 cites W2044197575 @default.
- W1974387743 cites W2047743167 @default.
- W1974387743 cites W2057118675 @default.
- W1974387743 cites W2058498059 @default.
- W1974387743 cites W2067926353 @default.
- W1974387743 cites W2079428856 @default.
- W1974387743 cites W2087646741 @default.
- W1974387743 cites W2089703377 @default.
- W1974387743 cites W2095412058 @default.
- W1974387743 cites W2163872172 @default.
- W1974387743 cites W3309237 @default.
- W1974387743 doi "https://doi.org/10.1539/joh.39.179" @default.
- W1974387743 hasPublicationYear "1997" @default.
- W1974387743 type Work @default.
- W1974387743 sameAs 1974387743 @default.
- W1974387743 citedByCount "44" @default.
- W1974387743 countsByYear W19743877432014 @default.
- W1974387743 countsByYear W19743877432016 @default.
- W1974387743 countsByYear W19743877432019 @default.
- W1974387743 countsByYear W19743877432020 @default.
- W1974387743 countsByYear W19743877432022 @default.
- W1974387743 countsByYear W19743877432023 @default.
- W1974387743 crossrefType "journal-article" @default.
- W1974387743 hasAuthorship W1974387743A5046784299 @default.
- W1974387743 hasAuthorship W1974387743A5059572624 @default.
- W1974387743 hasAuthorship W1974387743A5076994948 @default.
- W1974387743 hasBestOaLocation W19743877431 @default.
- W1974387743 hasConcept C126322002 @default.
- W1974387743 hasConcept C2779382419 @default.
- W1974387743 hasConcept C2780007613 @default.
- W1974387743 hasConcept C29730261 @default.
- W1974387743 hasConcept C33070731 @default.
- W1974387743 hasConcept C42407357 @default.
- W1974387743 hasConcept C71924100 @default.
- W1974387743 hasConcept C86803240 @default.
- W1974387743 hasConcept C99432707 @default.
- W1974387743 hasConceptScore W1974387743C126322002 @default.
- W1974387743 hasConceptScore W1974387743C2779382419 @default.
- W1974387743 hasConceptScore W1974387743C2780007613 @default.
- W1974387743 hasConceptScore W1974387743C29730261 @default.
- W1974387743 hasConceptScore W1974387743C33070731 @default.
- W1974387743 hasConceptScore W1974387743C42407357 @default.
- W1974387743 hasConceptScore W1974387743C71924100 @default.
- W1974387743 hasConceptScore W1974387743C86803240 @default.
- W1974387743 hasConceptScore W1974387743C99432707 @default.
- W1974387743 hasIssue "3" @default.
- W1974387743 hasLocation W19743877431 @default.
- W1974387743 hasOpenAccess W1974387743 @default.
- W1974387743 hasPrimaryLocation W19743877431 @default.
- W1974387743 hasRelatedWork W1490390872 @default.
- W1974387743 hasRelatedWork W1971999456 @default.
- W1974387743 hasRelatedWork W2019857045 @default.
- W1974387743 hasRelatedWork W2027723832 @default.
- W1974387743 hasRelatedWork W2072026014 @default.
- W1974387743 hasRelatedWork W2139002821 @default.
- W1974387743 hasRelatedWork W2894343251 @default.
- W1974387743 hasRelatedWork W4232022398 @default.
- W1974387743 hasRelatedWork W4240457743 @default.
- W1974387743 hasRelatedWork W820436367 @default.
- W1974387743 hasVolume "39" @default.
- W1974387743 isParatext "false" @default.
- W1974387743 isRetracted "false" @default.
- W1974387743 magId "1974387743" @default.
- W1974387743 workType "article" @default.