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• W1974389269 abstract "Despite its proven efficacy in reducing restenosis in selected lesions, one of the greatest uncertainties of coronary stenting is longer-term results associated with permanent placement of metallic prosthetic devices. To evaluate efficacy and safety in long-term, a prospective serial angiographic study at 6 months (mos), 1 year (yr) and 3 yrs was designed. Between June 1990 to July 1991, single Palmaz-Schatz stent implantation for native coronary arteries was successful in 94 patients (pts) (age: 63 ± 9, male 77%, multivessel disease: 49%) or 97 lesions (Ies) (LAD: 51%, RCA: 34%, Cx: 7%, LMCA: 8%, restenotic lesion: 54%, bail-out use: 24%). At 3 yrs, 93% of pts were alive, 88% free from death/MI/CABG and 79% free from death/MI/CABG/target lesion revascularization (TLR). Six mos follow-up angiography (FUA) was performed and cine films were available in 88 pts (94%). Nine pts (9.6%) underwent TLR and 3 pts died (cardiac: 1, non-cardiac: 2) within 12 mos. Excluding these 12 pts, 82 pts (85 les) were eligible for longer-term FU. FUA at 1 and 3 yrs was performed in 73 pts (89%), and 49 pts (60%), respectively. CAAS II was used for quantitative analysis. Pre Post 6 mos 1 yrs 3 yrs N of les 52 52 52 52 52 Interval (days) – – 193 ± 21 374 ± 24 1068 ± 105 MLD (mm) 1.00 ± 0.42 2.56 ± 0.5 1.98 ± 0.53 1.97 ± 0.52 2.12 ± 0.53 Ref (mm) 3.15 ± 0.58 3.42 ± 0.6 3.06 ± 0.6 3.07 ± 0.56 3.12 ± 0.56 MLD = minimal lumen diameter, Ref = Interpolated reference diameter MLD improved between 6 mos and 3 yrs (P = 0.016) and did not change between 6 mos and 1 yr. Clinical events beyond 1yr was analyzed in pts with or without FUA at 3 yrs. In 49 pts with FUA at 3 yrs, 2 pts (4%) suffered from MI unrelated to the stented les. TLR and PTCA for new les were required in 2 pts (4%) and 9 pts (18%) respectively. In 33 pts without FUA at 3 yrs, 3 pts (9%) died from definite non-cardiac causes and 2 pts (6%) underwent TLR due to angiographic restenosis at 1 yr FUA. In conclusion , safety and efficacy of stents appeared to be sustained at 3 yrs." @default.
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• W1974389269 date "1995-02-01" @default.
• W1974389269 modified "2023-09-26" @default.
• W1974389269 title "792-4 Three Years Clinical and Quantitative Angiographic Follow-up After the Palmaz-Schatz Coronary Stent Implantation" @default.
• W1974389269 doi "https://doi.org/10.1016/0735-1097(95)93014-4" @default.
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