FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1974421857> ?p ?o ?g. }

• W1974421857 endingPage "2368" @default.
• W1974421857 startingPage "2362" @default.
• W1974421857 abstract "In humans, mutations of the gene encoding for thyroid transcription factor-2 (TTF-2 or FOXE1) result in Bamforth syndrome. Bamforth syndrome is characterized by agenesis, cleft palate, spiky hair and choanal atresia. TTF-2 null mice (TTF-2(-/-) ) also exhibit cleft palate, suggesting its involvement in the palatogenesis. However, the molecular pathology and genetic regulation by TTF2 remain largely unknown. In the present study, the recombinant expression vector pBROAD3-TTF-2 containing the promoter of the mouse ROSA26 gene was created to form the structural gene of mouse TTF-2 and was microinjected into the male pronuclei of fertilized ova. Sequence analysis confirmed that the TTF-2 transgenic mouse model was established successfully. The transgenic mice displayed a phenotype of cleft palate. In addition, we found that TTF-2 was highly expressed in the medial edge epithelium (MEE) from the embryonic day 12.5 (E12.5) to E14.5 in TTF-2 transgenic mice. These observations suggest that overexpression of TTF-2 during palatogenesis may contribute to formation of cleft palate." @default.
• W1974421857 created "2016-06-24" @default.
• W1974421857 creator A5020076697 @default.
• W1974421857 creator A5021293751 @default.
• W1974421857 creator A5024993809 @default.
• W1974421857 creator A5029130019 @default.
• W1974421857 creator A5029918685 @default.
• W1974421857 creator A5052814363 @default.
• W1974421857 creator A5068258639 @default.
• W1974421857 creator A5082743889 @default.
• W1974421857 creator A5084693085 @default.
• W1974421857 date "2012-09-26" @default.
• W1974421857 modified "2023-09-23" @default.
• W1974421857 title "Overexpression of mouseTTF-2gene causes cleft palate" @default.
• W1974421857 cites W1493370386 @default.
• W1974421857 cites W1493582161 @default.
• W1974421857 cites W1496124518 @default.
• W1974421857 cites W1545219498 @default.
• W1974421857 cites W1965222408 @default.
• W1974421857 cites W1975059674 @default.
• W1974421857 cites W1981670738 @default.
• W1974421857 cites W1982912566 @default.
• W1974421857 cites W1987523473 @default.
• W1974421857 cites W2012678527 @default.
• W1974421857 cites W2029240437 @default.
• W1974421857 cites W2034044650 @default.
• W1974421857 cites W2035136671 @default.
• W1974421857 cites W2035757354 @default.
• W1974421857 cites W2037705608 @default.
• W1974421857 cites W2043503174 @default.
• W1974421857 cites W2046533586 @default.
• W1974421857 cites W2058682074 @default.
• W1974421857 cites W2064050439 @default.
• W1974421857 cites W2068313999 @default.
• W1974421857 cites W2081680395 @default.
• W1974421857 cites W2093831365 @default.
• W1974421857 cites W2094165314 @default.
• W1974421857 cites W2105168909 @default.
• W1974421857 cites W2109223747 @default.
• W1974421857 cites W2114235784 @default.
• W1974421857 cites W2118526247 @default.
• W1974421857 cites W2139074554 @default.
• W1974421857 cites W2145108229 @default.
• W1974421857 cites W2280133459 @default.
• W1974421857 cites W4212811418 @default.
• W1974421857 cites W4245322879 @default.
• W1974421857 doi "https://doi.org/10.1111/j.1582-4934.2012.01546.x" @default.
• W1974421857 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3823429" @default.
• W1974421857 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22304410" @default.
• W1974421857 hasPublicationYear "2012" @default.
• W1974421857 type Work @default.
• W1974421857 sameAs 1974421857 @default.
• W1974421857 citedByCount "12" @default.
• W1974421857 countsByYear W19744218572013 @default.
• W1974421857 countsByYear W19744218572014 @default.
• W1974421857 countsByYear W19744218572015 @default.
• W1974421857 countsByYear W19744218572016 @default.
• W1974421857 countsByYear W19744218572017 @default.
• W1974421857 countsByYear W19744218572019 @default.
• W1974421857 countsByYear W19744218572020 @default.
• W1974421857 crossrefType "journal-article" @default.
• W1974421857 hasAuthorship W1974421857A5020076697 @default.
• W1974421857 hasAuthorship W1974421857A5021293751 @default.
• W1974421857 hasAuthorship W1974421857A5024993809 @default.
• W1974421857 hasAuthorship W1974421857A5029130019 @default.
• W1974421857 hasAuthorship W1974421857A5029918685 @default.
• W1974421857 hasAuthorship W1974421857A5052814363 @default.
• W1974421857 hasAuthorship W1974421857A5068258639 @default.
• W1974421857 hasAuthorship W1974421857A5082743889 @default.
• W1974421857 hasAuthorship W1974421857A5084693085 @default.
• W1974421857 hasBestOaLocation W19744218571 @default.
• W1974421857 hasConcept C102230213 @default.
• W1974421857 hasConcept C104317684 @default.
• W1974421857 hasConcept C105702510 @default.
• W1974421857 hasConcept C110758877 @default.
• W1974421857 hasConcept C127716648 @default.
• W1974421857 hasConcept C141035611 @default.
• W1974421857 hasConcept C142724271 @default.
• W1974421857 hasConcept C153911025 @default.
• W1974421857 hasConcept C2780216207 @default.
• W1974421857 hasConcept C28748434 @default.
• W1974421857 hasConcept C54355233 @default.
• W1974421857 hasConcept C71924100 @default.
• W1974421857 hasConcept C86803240 @default.
• W1974421857 hasConcept C87073359 @default.
• W1974421857 hasConcept C95444343 @default.
• W1974421857 hasConceptScore W1974421857C102230213 @default.
• W1974421857 hasConceptScore W1974421857C104317684 @default.
• W1974421857 hasConceptScore W1974421857C105702510 @default.
• W1974421857 hasConceptScore W1974421857C110758877 @default.
• W1974421857 hasConceptScore W1974421857C127716648 @default.
• W1974421857 hasConceptScore W1974421857C141035611 @default.
• W1974421857 hasConceptScore W1974421857C142724271 @default.
• W1974421857 hasConceptScore W1974421857C153911025 @default.
• W1974421857 hasConceptScore W1974421857C2780216207 @default.
• W1974421857 hasConceptScore W1974421857C28748434 @default.
• W1974421857 hasConceptScore W1974421857C54355233 @default.
• W1974421857 hasConceptScore W1974421857C71924100 @default.

• next