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- W1974431763 abstract "~ CRITICAL role played by specific adhesion mol l. ecules in immune and inflammatory processes is being increasingly recognised and this has important implications for transplantation. Regulated adhesion between T cells and apposing cells is crucial for suc cessful antigen presentation and for the lysis of allo geneic target cells by cytotoxic T cells. The recruitment of leucocytes to the allograft is also adhesion-depend ent since binding to graft endothelium is the first, cru cial, step in emigration of circulating leucocytes into the graft. The wide range of adhesion molecules in volved in these processes opens up the possibility of new and complementary approaches to the develop ment of immunosuppressive treatments in transplan tation. There are three broad, related areas where anti adhesion molecule therapy might prove beneficial in clinical transplantation:" @default.
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- W1974431763 date "1995-08-01" @default.
- W1974431763 modified "2023-09-25" @default.
- W1974431763 title "Adhesion molecules and liver transplantation: new strategies for therapeutic intervention" @default.
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- W1974431763 doi "https://doi.org/10.1016/0168-8278(95)80340-8" @default.
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