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- W1974514717 abstract "Hydrogen sulphide is still a potential hazard in several occupations12 and especially in sulphate pulp mills (P J?ppinen, academic dissertation) and oil refineries. Blood sulphide may be used as an indicator of an excessive human hydrogen sulphide exposure. Fatal hydrogen sulphide concentrations are known.34 Blood sulphide concentrations have been determined before by ion selective electrodes combined with Con way microdiffusion cells but only high concentrations, 1-70-3-75 mg/1, in fatal cases could be detected by this method.4 Recently, the method using ion selective electrodes has been improved by preconcentration of trapped sulphide in sodium hydroxide solution.5 This new application allows blood sulphide determinations at low concen trations and it is thus suitable also for non-fatal hydrogen sulphide poisonings. Although decreased activities of haem synthesising enzymes, especially delta-aminolaevulinic acid syn thase (ALA-S) and haem synthase (Haem-S) have been reported to occur in workers exposed to hydrogen sulphide and methyl mercaptan,6 it has been difficult to assess the severity of hydrogen sulphide poisoning in non-fatal cases. The aim of the present work was to evaluate the usefulness of blood sulphide concentrations and activities of haem syn thesising enzymes in this respect." @default.
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- W1974514717 date "1990-04-01" @default.
- W1974514717 modified "2023-09-25" @default.
- W1974514717 title "Hydrogen sulphide poisoning: blood sulphide concentration and changes in haem metabolism." @default.
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- W1974514717 doi "https://doi.org/10.1136/oem.47.4.283" @default.
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