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- W1974524137 abstract "A bis-triazolyl phenylalaninyl galactoside was synthesized by a two-fold click reaction between an azido phenylalanine and a di-O-propynyl galactoside. By a cytotoxicity assay the compound was determined to be selectively toxic for multiple myeloma (MM) among a series of cancer cell lines with no toxicity to a control cell line. A Western blot analysis suggested that this compound could potentiate the cleavage of poly ADP-ribose polymerase in MM cells, leading to apoptosis." @default.
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- W1974524137 date "2014-07-01" @default.
- W1974524137 modified "2023-10-16" @default.
- W1974524137 title "Identification of a new bis-amino acid glycoside selectively toxic to multiple myeloma cells" @default.
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- W1974524137 doi "https://doi.org/10.1016/j.carres.2014.05.014" @default.
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