Matches in SemOpenAlex for { <https://semopenalex.org/work/W1974564489> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W1974564489 endingPage "576" @default.
- W1974564489 startingPage "569" @default.
- W1974564489 abstract "Twenty-one patients with relapsed or refractory germ cell tumors were treated with high-dose chemotherapy and marrow transplantation (HDC/BMT) from 1982–1993. Primary sites of disease were testis (17), ovary (three), and pineal gland (one). Pathology included dysgerminoma (one), choriocarcinoma with adenocarcinoma (one), seminoma (four), and nonseminoma or mixed germ cell tumor (15). Nineteen had at least two prior chemotherapy regimens and eight had cisplatin-refractory disease defined as progression within 4 weeks of a cycle of cisplatin-based chemotherapy. HDC regimens were mostly combinations of cyclophosphamide with etoposide and cisplatin or carboplatin. There were only two treatment-related deaths (aspergillosis and interstitial pneumonitis). Times to engraftment of granulocytes (21 ± 8.3 days) and platelets (32 ± 20.2 days) were reasonable with only the last nine patients receiving growth factors. At a minimum of 4 years follow-up, eight patients have died of disease, six of whom were cisplatin-refractory prior to transplant. Eleven patients (52% overall) are alive and continuously free of disease after 4–10 years including one of three with refractory ovarian germ cell tumor. HDC/BMT provides significant long-term disease-free survival as salvage therapy for both male and female relapsed germ cell tumor patients who are not refractory to cisplatin." @default.
- W1974564489 created "2016-06-24" @default.
- W1974564489 creator A5000560721 @default.
- W1974564489 creator A5029557109 @default.
- W1974564489 creator A5029559933 @default.
- W1974564489 creator A5031254185 @default.
- W1974564489 creator A5044568163 @default.
- W1974564489 date "1998-03-01" @default.
- W1974564489 modified "2023-10-06" @default.
- W1974564489 title "Long-term results of autologous marrow transplantation for relapsed or refractory male or female germ cell tumors" @default.
- W1974564489 cites W1573785776 @default.
- W1974564489 cites W1829527967 @default.
- W1974564489 cites W1909039587 @default.
- W1974564489 cites W1925062343 @default.
- W1974564489 cites W1934898490 @default.
- W1974564489 cites W1959252905 @default.
- W1974564489 cites W1967788921 @default.
- W1974564489 cites W1995297926 @default.
- W1974564489 cites W1995713981 @default.
- W1974564489 cites W2006420519 @default.
- W1974564489 cites W2041556755 @default.
- W1974564489 cites W2051675203 @default.
- W1974564489 cites W2054519925 @default.
- W1974564489 cites W2072619179 @default.
- W1974564489 cites W2124766378 @default.
- W1974564489 cites W2229089518 @default.
- W1974564489 cites W2405331095 @default.
- W1974564489 cites W2410855196 @default.
- W1974564489 cites W2424108965 @default.
- W1974564489 cites W44490522 @default.
- W1974564489 cites W82039293 @default.
- W1974564489 doi "https://doi.org/10.1038/sj.bmt.1701132" @default.
- W1974564489 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9543060" @default.
- W1974564489 hasPublicationYear "1998" @default.
- W1974564489 type Work @default.
- W1974564489 sameAs 1974564489 @default.
- W1974564489 citedByCount "26" @default.
- W1974564489 countsByYear W19745644892016 @default.
- W1974564489 countsByYear W19745644892020 @default.
- W1974564489 countsByYear W19745644892021 @default.
- W1974564489 crossrefType "journal-article" @default.
- W1974564489 hasAuthorship W1974564489A5000560721 @default.
- W1974564489 hasAuthorship W1974564489A5029557109 @default.
- W1974564489 hasAuthorship W1974564489A5029559933 @default.
- W1974564489 hasAuthorship W1974564489A5031254185 @default.
- W1974564489 hasAuthorship W1974564489A5044568163 @default.
- W1974564489 hasBestOaLocation W19745644891 @default.
- W1974564489 hasConcept C126322002 @default.
- W1974564489 hasConcept C141071460 @default.
- W1974564489 hasConcept C143998085 @default.
- W1974564489 hasConcept C2776252090 @default.
- W1974564489 hasConcept C2776694085 @default.
- W1974564489 hasConcept C2776755627 @default.
- W1974564489 hasConcept C2776938808 @default.
- W1974564489 hasConcept C2778119113 @default.
- W1974564489 hasConcept C2778239845 @default.
- W1974564489 hasConcept C2778324911 @default.
- W1974564489 hasConcept C2778895204 @default.
- W1974564489 hasConcept C2781451048 @default.
- W1974564489 hasConcept C2911091166 @default.
- W1974564489 hasConcept C71924100 @default.
- W1974564489 hasConcept C90924648 @default.
- W1974564489 hasConceptScore W1974564489C126322002 @default.
- W1974564489 hasConceptScore W1974564489C141071460 @default.
- W1974564489 hasConceptScore W1974564489C143998085 @default.
- W1974564489 hasConceptScore W1974564489C2776252090 @default.
- W1974564489 hasConceptScore W1974564489C2776694085 @default.
- W1974564489 hasConceptScore W1974564489C2776755627 @default.
- W1974564489 hasConceptScore W1974564489C2776938808 @default.
- W1974564489 hasConceptScore W1974564489C2778119113 @default.
- W1974564489 hasConceptScore W1974564489C2778239845 @default.
- W1974564489 hasConceptScore W1974564489C2778324911 @default.
- W1974564489 hasConceptScore W1974564489C2778895204 @default.
- W1974564489 hasConceptScore W1974564489C2781451048 @default.
- W1974564489 hasConceptScore W1974564489C2911091166 @default.
- W1974564489 hasConceptScore W1974564489C71924100 @default.
- W1974564489 hasConceptScore W1974564489C90924648 @default.
- W1974564489 hasIssue "6" @default.
- W1974564489 hasLocation W19745644891 @default.
- W1974564489 hasLocation W19745644892 @default.
- W1974564489 hasOpenAccess W1974564489 @default.
- W1974564489 hasPrimaryLocation W19745644891 @default.
- W1974564489 hasRelatedWork W1984775533 @default.
- W1974564489 hasRelatedWork W2025846087 @default.
- W1974564489 hasRelatedWork W2029688276 @default.
- W1974564489 hasRelatedWork W2049074931 @default.
- W1974564489 hasRelatedWork W2049680018 @default.
- W1974564489 hasRelatedWork W2142316271 @default.
- W1974564489 hasRelatedWork W2789166760 @default.
- W1974564489 hasRelatedWork W3109167642 @default.
- W1974564489 hasRelatedWork W4281769798 @default.
- W1974564489 hasRelatedWork W2133000900 @default.
- W1974564489 hasVolume "21" @default.
- W1974564489 isParatext "false" @default.
- W1974564489 isRetracted "false" @default.
- W1974564489 magId "1974564489" @default.
- W1974564489 workType "article" @default.