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- W1974577980 abstract "Purpose To compare multiple-electrode radiofrequency (RF) ablation versus RF ablation with a cluster electrode in an in vivo porcine kidney model. Materials and Methods Thirteen female pigs (mean weight, 45 kg) were used for the study. In each animal, RF ablations were performed for 12 minutes with a conventional cluster electrode in one kidney (controls, n = 13) and a multiple-electrode configuration in the contralateral organ. Multiple-electrode ablations were performed with electrodes 1.5 cm apart (group 1, n = 7) or 2.0 cm apart (group 2, n = 6). The mean maximum temperature at the electrode tips was determined. After each animal was euthanized, the kidneys were removed and the ablation zones were sectioned into 5-mm transverse slices. A representative slice was stained with 2,3,5-triphenyl-2H-tetrazolium chloride. Standard ablation zone metrics were measured and differences between groups were analyzed for statistical significance. Results The mean maximum ablation zone diameter was 3.0 cm ± 0.6 (SD) for controls, compared with 5.0 cm ± 0.5 for group 1 (P < .0001) and 4.4 cm ± 1.0 for group 2 (P = .002). Mean ablation zone minimum diameter was higher for group 1 (P = .002) and group 2 (P = .03) than for controls. Isoperimetric ratios were lowest for group 2 (P = .04 vs controls) whereas the highest temperatures at the electrode tips were observed with group 1 (P = .02 vs controls). Conclusion In normal porcine kidney, multiple-electrode RF ablation produced larger zones of ablation than a cluster electrode. Efficacy was greater when electrodes were spaced 1.5 cm apart than when they were spaced 2.0 cm apart. To compare multiple-electrode radiofrequency (RF) ablation versus RF ablation with a cluster electrode in an in vivo porcine kidney model. Thirteen female pigs (mean weight, 45 kg) were used for the study. In each animal, RF ablations were performed for 12 minutes with a conventional cluster electrode in one kidney (controls, n = 13) and a multiple-electrode configuration in the contralateral organ. Multiple-electrode ablations were performed with electrodes 1.5 cm apart (group 1, n = 7) or 2.0 cm apart (group 2, n = 6). The mean maximum temperature at the electrode tips was determined. After each animal was euthanized, the kidneys were removed and the ablation zones were sectioned into 5-mm transverse slices. A representative slice was stained with 2,3,5-triphenyl-2H-tetrazolium chloride. Standard ablation zone metrics were measured and differences between groups were analyzed for statistical significance. The mean maximum ablation zone diameter was 3.0 cm ± 0.6 (SD) for controls, compared with 5.0 cm ± 0.5 for group 1 (P < .0001) and 4.4 cm ± 1.0 for group 2 (P = .002). Mean ablation zone minimum diameter was higher for group 1 (P = .002) and group 2 (P = .03) than for controls. Isoperimetric ratios were lowest for group 2 (P = .04 vs controls) whereas the highest temperatures at the electrode tips were observed with group 1 (P = .02 vs controls). In normal porcine kidney, multiple-electrode RF ablation produced larger zones of ablation than a cluster electrode. Efficacy was greater when electrodes were spaced 1.5 cm apart than when they were spaced 2.0 cm apart." @default.
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- W1974577980 date "2007-08-01" @default.
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- W1974577980 title "Multiple-electrode Radiofrequency Ablation: Comparison with a Conventional Cluster Electrode in an In Vivo Porcine Kidney Model" @default.
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- W1974577980 doi "https://doi.org/10.1016/j.jvir.2007.05.010" @default.
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