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• W1974636523 abstract "We report on the responsiveness of a previously validated quality-of-life scale, the Quality of Life in Late-Stage Dementia scale (QUALID), as an outcome measure in a clinical trial of two psychotropic medications.Secondary analyses were conducted comparing outcome measures used in a randomized double-blind trial of two antipsychotics (olanzapine and risperidone) for the treatment of dementia-related behavioral symptoms. The QUALID was completed for 31 of the patients in addition to several measures of behavior-related dementia symptoms including the Neuropsychiatric Inventory, the Withdrawn Behavior subscale of the Multidimensional Observation Scale for Elderly Subjects, the Mini-Mental State Examination, and the Clinical Global Impression. Measures of safety and adverse effects included the Simpson-Angus Scale and records of specific adverse events.A significant positive relationship was found between QUALID score and improvement in behavioral symptoms, and a negative association was found with adverse medication effects.The QUALID was sensitive to both the treatment effects and the adverse effects of medication in this sample of patients." @default.
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• W1974636523 date "2005-01-01" @default.
• W1974636523 modified "2023-09-27" @default.
• W1974636523 title "Responsiveness of the Quality of Life in Late-Stage Dementia Scale to Psychotropic Drug Treatment in Late-Stage Dementia" @default.
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• W1974636523 doi "https://doi.org/10.1159/000082353" @default.
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