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- W1974647579 abstract "Tryptophan, 4-dimethylallyltryptophan, and various analogs of tryptophan were investigated for their effect on binding to cytochrome P-450 and on cytochrome P-450 and total alkaloid levels in Claviceps purpurea. These compounds were shown not to affect cytochrome P-450 levels, in contrast to phenobarbital which increased the levels, but rather exhibited stereospecific binding to cytochrome P-450. Those compounds (L-tryptophan and L-4-di-methylallyltryptophan), which showed the highest binding affinity and are known precursors, caused the greatest increase in total alkaloid levels. The significance of these findings is discussed." @default.
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- W1974647579 date "1970-08-01" @default.
- W1974647579 modified "2023-09-27" @default.
- W1974647579 title "Cytochrome P-450 and Alkaloid Synthesis in Claviceps Purpurea" @default.
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- W1974647579 doi "https://doi.org/10.1002/jps.2600590819" @default.
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