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- W1974676980 abstract "An initial SAR study on a series of apamin-displacing 2-aminothiazole KCa2 channel blockers is described. Potent inhibitors such as N-(4-methylpyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine (13) are disclosed, and for select members of the series, the relationship between the observed activity in a thallium flux, a binding and a whole-cell electrophysiology assay is presented." @default.
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- W1974676980 date "2008-10-01" @default.
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- W1974676980 title "Initial SAR studies on apamin-displacing 2-aminothiazole blockers of calcium-activated small conductance potassium channels" @default.
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- W1974676980 doi "https://doi.org/10.1016/j.bmcl.2008.08.023" @default.
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