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- W1974683963 abstract "Recently, urocortin(Ucn)2 and Ucn 3 showing high sequence homologies to corticotropin-releasing factor (CRF)have been discovered as members of CRF peptide family. Both peptides bind specifically to CRF2 receptor. We generated polyclonal antisera against Ucn 2 and Ucn 3 to define distribution patterns of these peptides in rat central nervous system. Many Ucn 2 neurons are present in both parvocellular and magnocellular divisions of the paraventricular nucleus(PVN)and a few Ucn 2 neurons exist in the supraoptic nucleus(SON)of the hypothalamus. Ucn 3 neurons exist in the rostral perifornical area between the fornix and the PVN, with a few cells found in the magnocellular division of the PVN. In the extra-hypothalamic region, Ucn 3 neurons are found in the dorsal division of the medial nucleus of the amygdala. These distribution patterns suggest distinct functions of Ucn 2 and Ucn 3 in the brain." @default.
- W1974683963 created "2016-06-24" @default.
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- W1974683963 date "2004-01-01" @default.
- W1974683963 modified "2023-09-26" @default.
- W1974683963 title "Distribution of Urocortin 2 and Urocortin 3 in Rat Brain" @default.
- W1974683963 cites W2028710649 @default.
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- W1974683963 doi "https://doi.org/10.1272/jnms.71.358" @default.
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