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- W1974715712 abstract "Clinically useful drugs target a relatively small number of proteins that lie within a clearly defined and chemically accessible space. However, many high value biological targets lie outside this chemical space, and an ability to access such ‘intractable’ targets not amenable to traditional small molecule intervention would expand treatment options and be a major boost for patients and the pharmaceutical industry. To date, success has been limited but new technologies and approaches are beginning to emerge that could provide novel lead generation capabilities that enable access to new drug target classes. We review these new approaches and their ability to provide the novel leads needed to tackle a new generation of biological targets." @default.
- W1974715712 created "2016-06-24" @default.
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- W1974715712 date "2013-03-01" @default.
- W1974715712 modified "2023-09-30" @default.
- W1974715712 title "Expanding medicinal chemistry space" @default.
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- W1974715712 cites W1969921890 @default.
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- W1974715712 cites W1979598348 @default.
- W1974715712 cites W1984554167 @default.
- W1974715712 cites W1994311174 @default.
- W1974715712 cites W1994848912 @default.
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- W1974715712 doi "https://doi.org/10.1016/j.drudis.2012.10.008" @default.
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