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- W1974767503 abstract "Abstract We propose a new quantitative method of establishing the biological relatedness of two organisms, by means of comparison of the experimentally observed, differential-melting-curves of their DNAs which are assumed to depend on the detailed structure of the corresponding base pair sequences. In the light of recent experimental and theoretical results discussed in this paper, this assumption seems to be well justified. In the case of viruses and bacteria, analysis of available experimental data, demonstrates the straightforward applicability of the method in quantitative determinations of relatedness. In spite of certain difficulties arising in the application of the method to eucaryotes, we believe that it still could serve in obtaining at least first-order estimates of eucaryotic relatedness." @default.
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- W1974767503 date "1980-09-01" @default.
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- W1974767503 title "Genetic distance: A simple quantitative measure of biological relatedness" @default.
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- W1974767503 doi "https://doi.org/10.1016/0022-5193(80)90071-5" @default.
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