Matches in SemOpenAlex for { <https://semopenalex.org/work/W1974776098> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W1974776098 endingPage "177" @default.
- W1974776098 startingPage "173" @default.
- W1974776098 abstract "When deprived of iron, Saccharomyces cerevisiae rearranges its metabolic flux towards increased glycerol production. This work examines the role and regulation of GPD1 and GPD2 , encoding two isoforms of glycerol 3‐phosphate dehydrogenase, in glycerol production during iron starvation. The two genes respond differently on transfer of cells to iron‐limited conditions. Whereas the expression of GPD2 increases about 3‐fold, that of GPD1 does not exhibit significant changes. Deletion of either GPD1 or GPD2 alters the capacity for glycerol production during iron‐limited as well as iron sufficient conditions. However, loss of function of either gene does not seem to provoke compensatory flux via the other gene product. As judged from the glycerol production, the amount produced by each single mutant adds approximately up to the level produced by the parental strain. In agreement with the pattern of expression of GPD2 , this gene product was estimated to account for the bulk of the glycerol production (about 60%) during iron‐limited conditions. The strong growth inhibition caused by iron starvation was reversed by the addition of iron also for a gpd1 Δ gpd2 Δ double deletion mutant, which is unable to produce any detectable glycerol." @default.
- W1974776098 created "2016-06-24" @default.
- W1974776098 creator A5001428915 @default.
- W1974776098 creator A5073416321 @default.
- W1974776098 date "1999-11-15" @default.
- W1974776098 modified "2023-10-05" @default.
- W1974776098 title "The effect of iron limitation on glycerol production and expression of the isogenes for NAD<sup>+</sup>-dependent glycerol 3-phosphate dehydrogenase in<i>Saccharomyces cerevisiae</i>" @default.
- W1974776098 cites W1563689661 @default.
- W1974776098 cites W1943102038 @default.
- W1974776098 cites W1968917541 @default.
- W1974776098 cites W1969060808 @default.
- W1974776098 cites W1987085324 @default.
- W1974776098 cites W2005806732 @default.
- W1974776098 cites W2018199071 @default.
- W1974776098 cites W2028709228 @default.
- W1974776098 cites W2036494644 @default.
- W1974776098 cites W2050742607 @default.
- W1974776098 cites W2058929656 @default.
- W1974776098 cites W2066743380 @default.
- W1974776098 cites W2074278834 @default.
- W1974776098 cites W2079588007 @default.
- W1974776098 cites W2088152932 @default.
- W1974776098 cites W2101442503 @default.
- W1974776098 cites W2123497663 @default.
- W1974776098 cites W2129951991 @default.
- W1974776098 cites W2140143127 @default.
- W1974776098 cites W2156469743 @default.
- W1974776098 cites W2219223708 @default.
- W1974776098 cites W4234317161 @default.
- W1974776098 cites W4248611027 @default.
- W1974776098 doi "https://doi.org/10.1016/s0014-5793(99)01456-8" @default.
- W1974776098 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10567692" @default.
- W1974776098 hasPublicationYear "1999" @default.
- W1974776098 type Work @default.
- W1974776098 sameAs 1974776098 @default.
- W1974776098 citedByCount "14" @default.
- W1974776098 countsByYear W19747760982013 @default.
- W1974776098 countsByYear W19747760982015 @default.
- W1974776098 countsByYear W19747760982017 @default.
- W1974776098 countsByYear W19747760982018 @default.
- W1974776098 countsByYear W19747760982020 @default.
- W1974776098 countsByYear W19747760982021 @default.
- W1974776098 crossrefType "journal-article" @default.
- W1974776098 hasAuthorship W1974776098A5001428915 @default.
- W1974776098 hasAuthorship W1974776098A5073416321 @default.
- W1974776098 hasBestOaLocation W19747760981 @default.
- W1974776098 hasConcept C100544194 @default.
- W1974776098 hasConcept C104317684 @default.
- W1974776098 hasConcept C143065580 @default.
- W1974776098 hasConcept C181199279 @default.
- W1974776098 hasConcept C185592680 @default.
- W1974776098 hasConcept C2776317432 @default.
- W1974776098 hasConcept C2777132085 @default.
- W1974776098 hasConcept C2777576037 @default.
- W1974776098 hasConcept C2780881558 @default.
- W1974776098 hasConcept C45566312 @default.
- W1974776098 hasConcept C55493867 @default.
- W1974776098 hasConcept C62231903 @default.
- W1974776098 hasConcept C75520062 @default.
- W1974776098 hasConcept C86803240 @default.
- W1974776098 hasConceptScore W1974776098C100544194 @default.
- W1974776098 hasConceptScore W1974776098C104317684 @default.
- W1974776098 hasConceptScore W1974776098C143065580 @default.
- W1974776098 hasConceptScore W1974776098C181199279 @default.
- W1974776098 hasConceptScore W1974776098C185592680 @default.
- W1974776098 hasConceptScore W1974776098C2776317432 @default.
- W1974776098 hasConceptScore W1974776098C2777132085 @default.
- W1974776098 hasConceptScore W1974776098C2777576037 @default.
- W1974776098 hasConceptScore W1974776098C2780881558 @default.
- W1974776098 hasConceptScore W1974776098C45566312 @default.
- W1974776098 hasConceptScore W1974776098C55493867 @default.
- W1974776098 hasConceptScore W1974776098C62231903 @default.
- W1974776098 hasConceptScore W1974776098C75520062 @default.
- W1974776098 hasConceptScore W1974776098C86803240 @default.
- W1974776098 hasIssue "3" @default.
- W1974776098 hasLocation W19747760981 @default.
- W1974776098 hasLocation W19747760982 @default.
- W1974776098 hasOpenAccess W1974776098 @default.
- W1974776098 hasPrimaryLocation W19747760981 @default.
- W1974776098 hasRelatedWork W1991911128 @default.
- W1974776098 hasRelatedWork W2019123127 @default.
- W1974776098 hasRelatedWork W2031722405 @default.
- W1974776098 hasRelatedWork W2033494319 @default.
- W1974776098 hasRelatedWork W2033578592 @default.
- W1974776098 hasRelatedWork W2037318596 @default.
- W1974776098 hasRelatedWork W2076799412 @default.
- W1974776098 hasRelatedWork W2085598782 @default.
- W1974776098 hasRelatedWork W2125900374 @default.
- W1974776098 hasRelatedWork W2168695178 @default.
- W1974776098 hasVolume "461" @default.
- W1974776098 isParatext "false" @default.
- W1974776098 isRetracted "false" @default.
- W1974776098 magId "1974776098" @default.
- W1974776098 workType "article" @default.