Matches in SemOpenAlex for { <https://semopenalex.org/work/W1974787010> ?p ?o ?g. }
- W1974787010 endingPage "60" @default.
- W1974787010 startingPage "55" @default.
- W1974787010 abstract "A cDNA clone, namely PtKPI, coding for a one-kazal domain serine proteinase inhibitor (SPI) was identified from haemocyte cDNA library of the swimming crab Portunus trituberculatus. It is the first kazal-type SPI reported from crabs, also the first one-kazal domain SPI in crustaceans. The full-length cDNA sequence was 683 bp and contained an open reading frame of 444 bp, 36 bp of 5′-untranslated region (UTR), and 203 bp of 3′-UTR with a poly(A) tail. It encoded a polypeptide of 147 amino acids with an estimated molecular mass of 15.85 kDa and a theoretical pI of 8.99. A signal peptide was defined at N-terminus with a putative cleavage site located after position 16 (GNA-YN). The domain of PtKPI with C-X3-C-X7-C-X6-Y-X3-C-X7-C-X12-C was similar to the consensus pattern of the kazal motif. One α-helix surrounded by an adjacent three-stranded β-sheet constructed the classical three-dimensional structure of kazal domain. PtKPI transcript was detected at a high level in the eyestalk and haemocytes that are involved in immune function. Upon challenge with three different microorganisms Vibrio alginolyticus, Micrococcus luteus and Pichia pastoris, the temporal expression of PtKPI in haemocytes showed different activation times against bacteria and fungi within an experimental period of 72 h. These results indicate that PtKPI is potentially involved in acute response against invading bacteria and fungi in P. trituberculatus." @default.
- W1974787010 created "2016-06-24" @default.
- W1974787010 creator A5004296607 @default.
- W1974787010 creator A5041490775 @default.
- W1974787010 creator A5046214153 @default.
- W1974787010 creator A5065776587 @default.
- W1974787010 creator A5068466330 @default.
- W1974787010 date "2012-08-01" @default.
- W1974787010 modified "2023-09-25" @default.
- W1974787010 title "The first kazal-type serine proteinase inhibitor in the swimming crab Portunus trituberculatus involved in immune response to bacteria and fungi" @default.
- W1974787010 cites W1952065778 @default.
- W1974787010 cites W1968222719 @default.
- W1974787010 cites W1976227473 @default.
- W1974787010 cites W1979164863 @default.
- W1974787010 cites W1980790461 @default.
- W1974787010 cites W1981978656 @default.
- W1974787010 cites W1983580669 @default.
- W1974787010 cites W1985154552 @default.
- W1974787010 cites W1998386900 @default.
- W1974787010 cites W2002268240 @default.
- W1974787010 cites W2003825981 @default.
- W1974787010 cites W2010444869 @default.
- W1974787010 cites W2011658131 @default.
- W1974787010 cites W2015015951 @default.
- W1974787010 cites W2018749577 @default.
- W1974787010 cites W2035210593 @default.
- W1974787010 cites W2035567217 @default.
- W1974787010 cites W2038783032 @default.
- W1974787010 cites W2041912408 @default.
- W1974787010 cites W2042206669 @default.
- W1974787010 cites W2051534955 @default.
- W1974787010 cites W2064778410 @default.
- W1974787010 cites W2070682210 @default.
- W1974787010 cites W2072517619 @default.
- W1974787010 cites W2079879986 @default.
- W1974787010 cites W2083581791 @default.
- W1974787010 cites W2093654784 @default.
- W1974787010 cites W2095473722 @default.
- W1974787010 cites W2107277218 @default.
- W1974787010 cites W2112218935 @default.
- W1974787010 cites W2112991219 @default.
- W1974787010 cites W2115718651 @default.
- W1974787010 cites W2124285343 @default.
- W1974787010 cites W2135191266 @default.
- W1974787010 cites W2140422547 @default.
- W1974787010 cites W2141540812 @default.
- W1974787010 cites W2151746312 @default.
- W1974787010 cites W2165616399 @default.
- W1974787010 cites W4251174927 @default.
- W1974787010 doi "https://doi.org/10.1016/j.aquaculture.2012.05.036" @default.
- W1974787010 hasPublicationYear "2012" @default.
- W1974787010 type Work @default.
- W1974787010 sameAs 1974787010 @default.
- W1974787010 citedByCount "12" @default.
- W1974787010 countsByYear W19747870102013 @default.
- W1974787010 countsByYear W19747870102014 @default.
- W1974787010 countsByYear W19747870102018 @default.
- W1974787010 countsByYear W19747870102019 @default.
- W1974787010 countsByYear W19747870102021 @default.
- W1974787010 countsByYear W19747870102023 @default.
- W1974787010 crossrefType "journal-article" @default.
- W1974787010 hasAuthorship W1974787010A5004296607 @default.
- W1974787010 hasAuthorship W1974787010A5041490775 @default.
- W1974787010 hasAuthorship W1974787010A5046214153 @default.
- W1974787010 hasAuthorship W1974787010A5065776587 @default.
- W1974787010 hasAuthorship W1974787010A5068466330 @default.
- W1974787010 hasConcept C104317684 @default.
- W1974787010 hasConcept C10858879 @default.
- W1974787010 hasConcept C153911025 @default.
- W1974787010 hasConcept C167625842 @default.
- W1974787010 hasConcept C181199279 @default.
- W1974787010 hasConcept C187882448 @default.
- W1974787010 hasConcept C2776154503 @default.
- W1974787010 hasConcept C2776714187 @default.
- W1974787010 hasConcept C2777807008 @default.
- W1974787010 hasConcept C2778066766 @default.
- W1974787010 hasConcept C2778968793 @default.
- W1974787010 hasConcept C47289529 @default.
- W1974787010 hasConcept C505870484 @default.
- W1974787010 hasConcept C523546767 @default.
- W1974787010 hasConcept C54355233 @default.
- W1974787010 hasConcept C55493867 @default.
- W1974787010 hasConcept C86803240 @default.
- W1974787010 hasConceptScore W1974787010C104317684 @default.
- W1974787010 hasConceptScore W1974787010C10858879 @default.
- W1974787010 hasConceptScore W1974787010C153911025 @default.
- W1974787010 hasConceptScore W1974787010C167625842 @default.
- W1974787010 hasConceptScore W1974787010C181199279 @default.
- W1974787010 hasConceptScore W1974787010C187882448 @default.
- W1974787010 hasConceptScore W1974787010C2776154503 @default.
- W1974787010 hasConceptScore W1974787010C2776714187 @default.
- W1974787010 hasConceptScore W1974787010C2777807008 @default.
- W1974787010 hasConceptScore W1974787010C2778066766 @default.
- W1974787010 hasConceptScore W1974787010C2778968793 @default.
- W1974787010 hasConceptScore W1974787010C47289529 @default.
- W1974787010 hasConceptScore W1974787010C505870484 @default.
- W1974787010 hasConceptScore W1974787010C523546767 @default.
- W1974787010 hasConceptScore W1974787010C54355233 @default.