Matches in SemOpenAlex for { <https://semopenalex.org/work/W1974807453> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W1974807453 endingPage "10681" @default.
- W1974807453 startingPage "10676" @default.
- W1974807453 abstract "Efficient enantioselective Cu-catalyzed allylic alkylations of aromatic and aliphatic allylic phosphates bearing di- and trisubstituted olefins are disclosed. Enantioselective C−C bond forming reactions are promoted in the presence of 10 mol % readily available chiral amino acid-based ligand (5 steps, 40% overall yield synthesis) and 5 mol % (CuOTf)2·C6H6. Reactions deliver tertiary and quaternary stereogenic carbon centers regioselectively and in 78−96% ee. Data regarding the effect of variations in ligand structure on the efficiency and enantioselectivity of the alkylation process, as well as a mechanistic working model, are presented. The suggested model involves a dual role for the chiral Cu complex: association of the Cu(I) center to the olefin is facilitated by a two-point binding between the carbonyl of the ligand's amide terminus and the PO of the substrate." @default.
- W1974807453 created "2016-06-24" @default.
- W1974807453 creator A5069279422 @default.
- W1974807453 creator A5081485832 @default.
- W1974807453 date "2004-08-07" @default.
- W1974807453 modified "2023-09-26" @default.
- W1974807453 title "Cu-Catalyzed Asymmetric Allylic Alkylations of Aromatic and Aliphatic Phosphates with Alkylzinc Reagents. An Effective Method for Enantioselective Synthesis of Tertiary and Quaternary Carbons" @default.
- W1974807453 cites W1995313867 @default.
- W1974807453 cites W2016037820 @default.
- W1974807453 cites W2033695089 @default.
- W1974807453 cites W2033799109 @default.
- W1974807453 cites W2035586374 @default.
- W1974807453 cites W2068580249 @default.
- W1974807453 cites W2069621987 @default.
- W1974807453 cites W2130298078 @default.
- W1974807453 cites W2131217125 @default.
- W1974807453 cites W2144963538 @default.
- W1974807453 cites W2145807732 @default.
- W1974807453 cites W2162898894 @default.
- W1974807453 cites W2333643197 @default.
- W1974807453 cites W2951641618 @default.
- W1974807453 cites W2952374586 @default.
- W1974807453 cites W2953392070 @default.
- W1974807453 doi "https://doi.org/10.1021/ja0478779" @default.
- W1974807453 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15327326" @default.
- W1974807453 hasPublicationYear "2004" @default.
- W1974807453 type Work @default.
- W1974807453 sameAs 1974807453 @default.
- W1974807453 citedByCount "140" @default.
- W1974807453 countsByYear W19748074532012 @default.
- W1974807453 countsByYear W19748074532013 @default.
- W1974807453 countsByYear W19748074532014 @default.
- W1974807453 countsByYear W19748074532015 @default.
- W1974807453 countsByYear W19748074532016 @default.
- W1974807453 countsByYear W19748074532017 @default.
- W1974807453 countsByYear W19748074532018 @default.
- W1974807453 countsByYear W19748074532019 @default.
- W1974807453 countsByYear W19748074532020 @default.
- W1974807453 countsByYear W19748074532021 @default.
- W1974807453 countsByYear W19748074532022 @default.
- W1974807453 countsByYear W19748074532023 @default.
- W1974807453 crossrefType "journal-article" @default.
- W1974807453 hasAuthorship W1974807453A5069279422 @default.
- W1974807453 hasAuthorship W1974807453A5081485832 @default.
- W1974807453 hasConcept C116569031 @default.
- W1974807453 hasConcept C120095180 @default.
- W1974807453 hasConcept C134195300 @default.
- W1974807453 hasConcept C146686406 @default.
- W1974807453 hasConcept C155647269 @default.
- W1974807453 hasConcept C161790260 @default.
- W1974807453 hasConcept C164361826 @default.
- W1974807453 hasConcept C170493617 @default.
- W1974807453 hasConcept C178790620 @default.
- W1974807453 hasConcept C185592680 @default.
- W1974807453 hasConcept C21951064 @default.
- W1974807453 hasConcept C27083343 @default.
- W1974807453 hasConcept C2778439535 @default.
- W1974807453 hasConcept C51886252 @default.
- W1974807453 hasConcept C55493867 @default.
- W1974807453 hasConcept C71240020 @default.
- W1974807453 hasConceptScore W1974807453C116569031 @default.
- W1974807453 hasConceptScore W1974807453C120095180 @default.
- W1974807453 hasConceptScore W1974807453C134195300 @default.
- W1974807453 hasConceptScore W1974807453C146686406 @default.
- W1974807453 hasConceptScore W1974807453C155647269 @default.
- W1974807453 hasConceptScore W1974807453C161790260 @default.
- W1974807453 hasConceptScore W1974807453C164361826 @default.
- W1974807453 hasConceptScore W1974807453C170493617 @default.
- W1974807453 hasConceptScore W1974807453C178790620 @default.
- W1974807453 hasConceptScore W1974807453C185592680 @default.
- W1974807453 hasConceptScore W1974807453C21951064 @default.
- W1974807453 hasConceptScore W1974807453C27083343 @default.
- W1974807453 hasConceptScore W1974807453C2778439535 @default.
- W1974807453 hasConceptScore W1974807453C51886252 @default.
- W1974807453 hasConceptScore W1974807453C55493867 @default.
- W1974807453 hasConceptScore W1974807453C71240020 @default.
- W1974807453 hasIssue "34" @default.
- W1974807453 hasLocation W19748074531 @default.
- W1974807453 hasLocation W19748074532 @default.
- W1974807453 hasOpenAccess W1974807453 @default.
- W1974807453 hasPrimaryLocation W19748074531 @default.
- W1974807453 hasRelatedWork W1974807453 @default.
- W1974807453 hasRelatedWork W2032314444 @default.
- W1974807453 hasRelatedWork W2106196516 @default.
- W1974807453 hasRelatedWork W2167251002 @default.
- W1974807453 hasRelatedWork W2169047584 @default.
- W1974807453 hasRelatedWork W2554305846 @default.
- W1974807453 hasRelatedWork W2754468957 @default.
- W1974807453 hasRelatedWork W2936612026 @default.
- W1974807453 hasRelatedWork W3033006580 @default.
- W1974807453 hasRelatedWork W4237032493 @default.
- W1974807453 hasVolume "126" @default.
- W1974807453 isParatext "false" @default.
- W1974807453 isRetracted "false" @default.
- W1974807453 magId "1974807453" @default.
- W1974807453 workType "article" @default.