FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1974837148> ?p ?o ?g. }

• W1974837148 endingPage "e14616" @default.
• W1974837148 startingPage "e14616" @default.
• W1974837148 abstract "Vogt-Koyanagi-Harada (VKH) syndrome is a systemic autoimmune disease. CD4(+) T cells have been shown to be involved in autoimmune diseases including VKH syndrome. To screen aberrantly expressed membrane proteins in CD4(+) T cell from patients with active VKH syndrome, blood samples were taken from five patients with active VKH syndrome and five healthy individuals. A label-free quantitative proteomic strategy was used to identify the differently expressed proteins between the two groups. The results revealed that the expression of 102 peptides was significantly altered (p<0.05) between two groups and matched amino acid sequences of proteins deposited in the international protein index (ipi.HUMAN.v3.36.fasta). The identified peptides corresponded to 64 proteins, in which 30 showed more than a 1.5-fold difference between the two groups. The decreased expression of CD18 and AKNA transcription factor (AKNA), both being three-fold lower than controls in expression identified by the label-free method, was further confirmed in an additional group of five active VKH patients and six normal individuals using the Western blot technique. A significantly decreased expression of CD18 and AKNA suggests a role for both proteins in the pathogenesis of this syndrome." @default.
• W1974837148 created "2016-06-24" @default.
• W1974837148 creator A5000508996 @default.
• W1974837148 creator A5005016013 @default.
• W1974837148 creator A5007999612 @default.
• W1974837148 creator A5036936453 @default.
• W1974837148 creator A5073363235 @default.
• W1974837148 date "2011-01-28" @default.
• W1974837148 modified "2023-09-25" @default.
• W1974837148 title "Label-Free Proteomics Reveals Decreased Expression of CD18 and AKNA in Peripheral CD4+ T Cells from Patients with Vogt-Koyanagi-Harada Syndrome" @default.
• W1974837148 cites W1559143809 @default.
• W1974837148 cites W1565577065 @default.
• W1974837148 cites W1584880758 @default.
• W1974837148 cites W1598598707 @default.
• W1974837148 cites W1624592617 @default.
• W1974837148 cites W1645222688 @default.
• W1974837148 cites W1748312647 @default.
• W1974837148 cites W1964537925 @default.
• W1974837148 cites W1964960008 @default.
• W1974837148 cites W1965614739 @default.
• W1974837148 cites W1977603836 @default.
• W1974837148 cites W1989959418 @default.
• W1974837148 cites W1990815293 @default.
• W1974837148 cites W2004199488 @default.
• W1974837148 cites W2007772670 @default.
• W1974837148 cites W2010671048 @default.
• W1974837148 cites W2023121129 @default.
• W1974837148 cites W2029113441 @default.
• W1974837148 cites W2035382483 @default.
• W1974837148 cites W2038152129 @default.
• W1974837148 cites W2048333869 @default.
• W1974837148 cites W2048533652 @default.
• W1974837148 cites W2050337641 @default.
• W1974837148 cites W2054341098 @default.
• W1974837148 cites W2056182246 @default.
• W1974837148 cites W2061797968 @default.
• W1974837148 cites W2077985212 @default.
• W1974837148 cites W2082780532 @default.
• W1974837148 cites W2089813874 @default.
• W1974837148 cites W2093797047 @default.
• W1974837148 cites W2096057003 @default.
• W1974837148 cites W2119464357 @default.
• W1974837148 cites W2125544442 @default.
• W1974837148 cites W2140453892 @default.
• W1974837148 cites W2143391236 @default.
• W1974837148 cites W2150015438 @default.
• W1974837148 cites W2161374993 @default.
• W1974837148 cites W2170400730 @default.
• W1974837148 cites W2170717423 @default.
• W1974837148 cites W2321416702 @default.
• W1974837148 cites W2336843185 @default.
• W1974837148 cites W2394126402 @default.
• W1974837148 cites W2419271155 @default.
• W1974837148 doi "https://doi.org/10.1371/journal.pone.0014616" @default.
• W1974837148 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3050983" @default.
• W1974837148 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21297967" @default.
• W1974837148 hasPublicationYear "2011" @default.
• W1974837148 type Work @default.
• W1974837148 sameAs 1974837148 @default.
• W1974837148 citedByCount "19" @default.
• W1974837148 countsByYear W19748371482012 @default.
• W1974837148 countsByYear W19748371482013 @default.
• W1974837148 countsByYear W19748371482014 @default.
• W1974837148 countsByYear W19748371482017 @default.
• W1974837148 countsByYear W19748371482018 @default.
• W1974837148 countsByYear W19748371482019 @default.
• W1974837148 countsByYear W19748371482020 @default.
• W1974837148 countsByYear W19748371482022 @default.
• W1974837148 countsByYear W19748371482023 @default.
• W1974837148 crossrefType "journal-article" @default.
• W1974837148 hasAuthorship W1974837148A5000508996 @default.
• W1974837148 hasAuthorship W1974837148A5005016013 @default.
• W1974837148 hasAuthorship W1974837148A5007999612 @default.
• W1974837148 hasAuthorship W1974837148A5036936453 @default.
• W1974837148 hasAuthorship W1974837148A5073363235 @default.
• W1974837148 hasBestOaLocation W19748371481 @default.
• W1974837148 hasConcept C104317684 @default.
• W1974837148 hasConcept C150194340 @default.
• W1974837148 hasConcept C153911025 @default.
• W1974837148 hasConcept C203014093 @default.
• W1974837148 hasConcept C2776415932 @default.
• W1974837148 hasConcept C2780942790 @default.
• W1974837148 hasConcept C46111723 @default.
• W1974837148 hasConcept C55493867 @default.
• W1974837148 hasConcept C71924100 @default.
• W1974837148 hasConcept C86803240 @default.
• W1974837148 hasConceptScore W1974837148C104317684 @default.
• W1974837148 hasConceptScore W1974837148C150194340 @default.
• W1974837148 hasConceptScore W1974837148C153911025 @default.
• W1974837148 hasConceptScore W1974837148C203014093 @default.
• W1974837148 hasConceptScore W1974837148C2776415932 @default.
• W1974837148 hasConceptScore W1974837148C2780942790 @default.
• W1974837148 hasConceptScore W1974837148C46111723 @default.
• W1974837148 hasConceptScore W1974837148C55493867 @default.
• W1974837148 hasConceptScore W1974837148C71924100 @default.
• W1974837148 hasConceptScore W1974837148C86803240 @default.
• W1974837148 hasIssue "1" @default.
• W1974837148 hasLocation W19748371481 @default.

• next