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- W1974876994 abstract "1. Using dog liver microsomal preparations, we have isolated and identified a new metabolite of aflatoxicol, aflatoxicol M1; this metabolic transformation is analogous to the conversion of aflatoxin B1 to aflatoxin M1.2. Aflatoxicol M1 can also be produced from aflatoxin M1 by a reductase present in rabbit liver cytosol, a reaction analogous to the reduction of aflatoxin B1 to aflatoxicol.3. In addition, aflatoxicol M1 can be oxidized to aflatoxin M1 by a carbon monoxide-insensitive dehydrogenase activity associated with human liver microsomes, a reaction analogous to the production of aflatoxin B1 from aflatoxicol by this fraction.4. Ultra-violet, fluorescence, and mass spectral characteristics of aflatoxicol M1 are described.5. The significance of this new aflatoxin metabolite and the possibility that it may be biologically active are discussed." @default.
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- W1974876994 date "1977-01-01" @default.
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- W1974876994 title "Aflatoxicol M<sub>1</sub>, A New Metabolite of Aflatoxicol" @default.
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- W1974876994 doi "https://doi.org/10.3109/00498257709035799" @default.
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