FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1974888049> ?p ?o ?g. }

• W1974888049 endingPage "421" @default.
• W1974888049 startingPage "417" @default.
• W1974888049 abstract "The reaction of 3,5-dimethoxybenzyl trimethylsilyl ether (3) with different aldehydes (n-PrCHO, n-C(11)H(23)CHO, MeCHO, PhCHO) in the presence of lithium powder and a catalytic amount of naphthalene (4 mol %) gave, after hydrolysis, the expected alcohols 4 in moderate yields. The dehydroxylation of these compounds through the corresponding mesylates 5 or directly from benzylic derivatives by catalytic hydrogenation, afforded compounds 6, which are finally demethylated to yield 5-alkyl-3,5-dihydroxyresorcinols, such as olivetol (7a), grevillol (7b), 1,3-dihydroxy-5-propylbenzene (7c), or dihydropinosilvine (7d). Dehydration of alcohol derivatives 4 followed by demethylation led to hydroxylated stilbene-type structures, such as pinosilvine (9d), resveratrol (9e), or piceatannol (9f), which in some cases can be hydrogenated to give saturated molecules such as combretastanin B-4 tetramethyl ether (6f) or chrysotobibenzyl (6g). Finally, when the naphthalene-catalyzed lithiation of compound 3 was performed in the presence of other electrophiles [Me(3)SiCl, t-BuCHO, CH(3)(CH(2))(4)CHO, 4-Me(3)SiOC(6)H(4)CHO, (CH(2))(5)CO, PhN=C=O, PhN=CHPh], the expected reaction products 12 were isolated, after hydrolysis." @default.
• W1974888049 created "2016-06-24" @default.
• W1974888049 creator A5021779359 @default.
• W1974888049 creator A5026767062 @default.
• W1974888049 creator A5040276834 @default.
• W1974888049 date "1997-01-01" @default.
• W1974888049 modified "2023-10-17" @default.
• W1974888049 title "Simple Synthesis of 5-Substituted Resorcinols: A Revisited Family of Interesting Bioactive Molecules" @default.
• W1974888049 cites W1563769776 @default.
• W1974888049 cites W1964249806 @default.
• W1974888049 cites W1965607933 @default.
• W1974888049 cites W1973594457 @default.
• W1974888049 cites W1974170121 @default.
• W1974888049 cites W1976216957 @default.
• W1974888049 cites W1976991366 @default.
• W1974888049 cites W1977836705 @default.
• W1974888049 cites W1980627177 @default.
• W1974888049 cites W1991021747 @default.
• W1974888049 cites W1995438187 @default.
• W1974888049 cites W2000984931 @default.
• W1974888049 cites W2009939738 @default.
• W1974888049 cites W2010129953 @default.
• W1974888049 cites W2023638561 @default.
• W1974888049 cites W2023711810 @default.
• W1974888049 cites W2028002837 @default.
• W1974888049 cites W2040726375 @default.
• W1974888049 cites W2066592345 @default.
• W1974888049 cites W2084300131 @default.
• W1974888049 cites W2086398385 @default.
• W1974888049 cites W2089928496 @default.
• W1974888049 cites W2949720592 @default.
• W1974888049 cites W2949897140 @default.
• W1974888049 cites W2950286194 @default.
• W1974888049 cites W2951994662 @default.
• W1974888049 cites W2952740382 @default.
• W1974888049 cites W2952952897 @default.
• W1974888049 cites W2953091407 @default.
• W1974888049 cites W4234998182 @default.
• W1974888049 doi "https://doi.org/10.1021/jo9610624" @default.
• W1974888049 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11671418" @default.
• W1974888049 hasPublicationYear "1997" @default.
• W1974888049 type Work @default.
• W1974888049 sameAs 1974888049 @default.
• W1974888049 citedByCount "84" @default.
• W1974888049 countsByYear W19748880492012 @default.
• W1974888049 countsByYear W19748880492013 @default.
• W1974888049 countsByYear W19748880492014 @default.
• W1974888049 countsByYear W19748880492015 @default.
• W1974888049 countsByYear W19748880492016 @default.
• W1974888049 countsByYear W19748880492017 @default.
• W1974888049 countsByYear W19748880492018 @default.
• W1974888049 countsByYear W19748880492019 @default.
• W1974888049 countsByYear W19748880492021 @default.
• W1974888049 countsByYear W19748880492022 @default.
• W1974888049 countsByYear W19748880492023 @default.
• W1974888049 crossrefType "journal-article" @default.
• W1974888049 hasAuthorship W1974888049A5021779359 @default.
• W1974888049 hasAuthorship W1974888049A5026767062 @default.
• W1974888049 hasAuthorship W1974888049A5040276834 @default.
• W1974888049 hasConcept C104317684 @default.
• W1974888049 hasConcept C150194340 @default.
• W1974888049 hasConcept C155647269 @default.
• W1974888049 hasConcept C161790260 @default.
• W1974888049 hasConcept C178790620 @default.
• W1974888049 hasConcept C181886296 @default.
• W1974888049 hasConcept C185592680 @default.
• W1974888049 hasConcept C190727270 @default.
• W1974888049 hasConcept C202199734 @default.
• W1974888049 hasConcept C2777000832 @default.
• W1974888049 hasConcept C2779255514 @default.
• W1974888049 hasConcept C2780407432 @default.
• W1974888049 hasConcept C2781066024 @default.
• W1974888049 hasConcept C50027330 @default.
• W1974888049 hasConcept C55493867 @default.
• W1974888049 hasConcept C94412978 @default.
• W1974888049 hasConceptScore W1974888049C104317684 @default.
• W1974888049 hasConceptScore W1974888049C150194340 @default.
• W1974888049 hasConceptScore W1974888049C155647269 @default.
• W1974888049 hasConceptScore W1974888049C161790260 @default.
• W1974888049 hasConceptScore W1974888049C178790620 @default.
• W1974888049 hasConceptScore W1974888049C181886296 @default.
• W1974888049 hasConceptScore W1974888049C185592680 @default.
• W1974888049 hasConceptScore W1974888049C190727270 @default.
• W1974888049 hasConceptScore W1974888049C202199734 @default.
• W1974888049 hasConceptScore W1974888049C2777000832 @default.
• W1974888049 hasConceptScore W1974888049C2779255514 @default.
• W1974888049 hasConceptScore W1974888049C2780407432 @default.
• W1974888049 hasConceptScore W1974888049C2781066024 @default.
• W1974888049 hasConceptScore W1974888049C50027330 @default.
• W1974888049 hasConceptScore W1974888049C55493867 @default.
• W1974888049 hasConceptScore W1974888049C94412978 @default.
• W1974888049 hasIssue "2" @default.
• W1974888049 hasLocation W19748880491 @default.
• W1974888049 hasLocation W19748880492 @default.
• W1974888049 hasOpenAccess W1974888049 @default.
• W1974888049 hasPrimaryLocation W19748880491 @default.
• W1974888049 hasRelatedWork W2073046392 @default.
• W1974888049 hasRelatedWork W2288697188 @default.

• next