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- W1974890059 abstract "Abstract A sandwich antigen capture assay using a double monoclonal antibody system revealed the presence of lipoarabinomannan (LAM) antigen in about 25% of the serum samples in subjects with pulmonary tuberculosis and tuberculoid leprosy. Lepromatous leprosy sera showed about 40% antigen positivity. Anti-LAM antibodies could be detected in about 90% of subjects with pulmonary tuberculosis and lepromatous leprosy. However in tuberculoid leprosy sera anti-LAM antibodies were positive in only 22% of the patients. Antigen and antibody levels in pulmonary tuberculosis and lepromatous leprosy declined steadily during anti-mycobacterial therapy, whereas in the tuberculoid type leprosy a distinct increase in antibody positivity was noticed. The high percentage of anti-LAM antibodies in pulmonary tuberculosis subjects may be of diagnostic significance." @default.
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- W1974890059 date "1995-06-01" @default.
- W1974890059 modified "2023-09-22" @default.
- W1974890059 title "Lipoarabinomannan antigen and anti-lipoarabinomannan antibody profile in the serum of patients with mycobacterial infections and their significance in disease process" @default.
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- W1974890059 doi "https://doi.org/10.1016/0888-0786(95)95346-r" @default.
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