FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1974891005> ?p ?o ?g. }

• W1974891005 endingPage "795" @default.
• W1974891005 startingPage "788" @default.
• W1974891005 abstract "Recent studies show that prolonged (eg, 24-hour) postischemic hypothermia confers lasting histological and behavioral protection against severe global cerebral ischemia. However, functional abnormalities may be compensated for by undamaged brain regions and thus not detected by behavioral tests. To determine whether hypothermia preserves CA1 functional integrity, we measured synaptic and membrane properties of CA1 neurons in ischemic gerbils treated with postischemic hypothermia.Gerbils were subjected to 5 minutes of forebrain ischemia and were either left untreated or exposed to 2 days of hypothermia (32 degrees C for 24 hours and then 34 degrees C for 24 hours). Sham animals were operated on but not made ischemic, then either allowed to recover at room temperature or subjected to hypothermia for 2 days. Approximately 5 weeks after ischemia or sham surgery, patch-clamp recordings were obtained from the CA1 region of hippocampal slices.There was approximately 95% CA1 cell loss in untreated ischemic animals, whereas ischemic gerbils treated with hypothermia had cell counts similar to sham animals. Resting membrane potential, action potential amplitude and duration, input resistance, and synaptic currents evoked by Schaffer collateral stimulation were similar between pyramidal cells obtained from ischemic gerbils treated with hypothermia and sham-operated animals (P:>0.05).These data demonstrate that postischemic hypothermia preserves the measured electrophysiological properties of CA1 neurons in the absence of any apparent functional abnormalities. This study provides further support for the use of hypothermia as a treatment for cerebral ischemia." @default.
• W1974891005 created "2016-06-24" @default.
• W1974891005 creator A5016510515 @default.
• W1974891005 creator A5019840028 @default.
• W1974891005 creator A5047765476 @default.
• W1974891005 creator A5053257075 @default.
• W1974891005 creator A5060268592 @default.
• W1974891005 date "2001-03-01" @default.
• W1974891005 modified "2023-10-18" @default.
• W1974891005 title "Electrophysiological Properties of CA1 Neurons Protected by Postischemic Hypothermia in Gerbils" @default.
• W1974891005 cites W114528988 @default.
• W1974891005 cites W1667970511 @default.
• W1974891005 cites W1976329162 @default.
• W1974891005 cites W1980286368 @default.
• W1974891005 cites W1983452327 @default.
• W1974891005 cites W1989700367 @default.
• W1974891005 cites W1990835357 @default.
• W1974891005 cites W1992363855 @default.
• W1974891005 cites W1996057550 @default.
• W1974891005 cites W1998079511 @default.
• W1974891005 cites W2002360249 @default.
• W1974891005 cites W2005304266 @default.
• W1974891005 cites W2013877892 @default.
• W1974891005 cites W2035750459 @default.
• W1974891005 cites W2044393186 @default.
• W1974891005 cites W2049312316 @default.
• W1974891005 cites W2060249985 @default.
• W1974891005 cites W2060418060 @default.
• W1974891005 cites W2075453867 @default.
• W1974891005 cites W2077307937 @default.
• W1974891005 cites W2088127441 @default.
• W1974891005 cites W2093421851 @default.
• W1974891005 cites W2112763282 @default.
• W1974891005 cites W2118740391 @default.
• W1974891005 cites W2121087310 @default.
• W1974891005 cites W2129648625 @default.
• W1974891005 cites W2157645771 @default.
• W1974891005 cites W2157945907 @default.
• W1974891005 cites W2169079203 @default.
• W1974891005 cites W2407640022 @default.
• W1974891005 cites W2439953398 @default.
• W1974891005 cites W4301403555 @default.
• W1974891005 doi "https://doi.org/10.1161/01.str.32.3.788" @default.
• W1974891005 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11239203" @default.
• W1974891005 hasPublicationYear "2001" @default.
• W1974891005 type Work @default.
• W1974891005 sameAs 1974891005 @default.
• W1974891005 citedByCount "23" @default.
• W1974891005 countsByYear W19748910052012 @default.
• W1974891005 countsByYear W19748910052013 @default.
• W1974891005 countsByYear W19748910052015 @default.
• W1974891005 countsByYear W19748910052017 @default.
• W1974891005 countsByYear W19748910052019 @default.
• W1974891005 crossrefType "journal-article" @default.
• W1974891005 hasAuthorship W1974891005A5016510515 @default.
• W1974891005 hasAuthorship W1974891005A5019840028 @default.
• W1974891005 hasAuthorship W1974891005A5047765476 @default.
• W1974891005 hasAuthorship W1974891005A5053257075 @default.
• W1974891005 hasAuthorship W1974891005A5060268592 @default.
• W1974891005 hasBestOaLocation W19748910051 @default.
• W1974891005 hasConcept C126322002 @default.
• W1974891005 hasConcept C148762608 @default.
• W1974891005 hasConcept C170493617 @default.
• W1974891005 hasConcept C185263204 @default.
• W1974891005 hasConcept C25274449 @default.
• W1974891005 hasConcept C2777390192 @default.
• W1974891005 hasConcept C2778039732 @default.
• W1974891005 hasConcept C2778820722 @default.
• W1974891005 hasConcept C2780222073 @default.
• W1974891005 hasConcept C42219234 @default.
• W1974891005 hasConcept C541997718 @default.
• W1974891005 hasConcept C71924100 @default.
• W1974891005 hasConceptScore W1974891005C126322002 @default.
• W1974891005 hasConceptScore W1974891005C148762608 @default.
• W1974891005 hasConceptScore W1974891005C170493617 @default.
• W1974891005 hasConceptScore W1974891005C185263204 @default.
• W1974891005 hasConceptScore W1974891005C25274449 @default.
• W1974891005 hasConceptScore W1974891005C2777390192 @default.
• W1974891005 hasConceptScore W1974891005C2778039732 @default.
• W1974891005 hasConceptScore W1974891005C2778820722 @default.
• W1974891005 hasConceptScore W1974891005C2780222073 @default.
• W1974891005 hasConceptScore W1974891005C42219234 @default.
• W1974891005 hasConceptScore W1974891005C541997718 @default.
• W1974891005 hasConceptScore W1974891005C71924100 @default.
• W1974891005 hasIssue "3" @default.
• W1974891005 hasLocation W19748910051 @default.
• W1974891005 hasLocation W19748910052 @default.
• W1974891005 hasLocation W19748910053 @default.
• W1974891005 hasOpenAccess W1974891005 @default.
• W1974891005 hasPrimaryLocation W19748910051 @default.
• W1974891005 hasRelatedWork W1969863703 @default.
• W1974891005 hasRelatedWork W1974891005 @default.
• W1974891005 hasRelatedWork W2001107596 @default.
• W1974891005 hasRelatedWork W2112763282 @default.
• W1974891005 hasRelatedWork W2150569619 @default.
• W1974891005 hasRelatedWork W2367954244 @default.
• W1974891005 hasRelatedWork W2383593562 @default.
• W1974891005 hasRelatedWork W2949055990 @default.

• next