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- W1974910439 abstract "THE DEVELOPMENT of a hemorrhagic diathesis following an open-heart operation is a serious complication. 1 Hemorrhagic disease may develop as a function of: (1) abnormalities directly related to extracorporeal circulation such as thrombocytopenia, defibrination, or fibrinolysis, 2 (2) depressed coagulation factors associated with hepatic decompensation, (3) occult thrombocytopenia occurring in the setting of congestive splenomegaly or drug purpura, 3 and (4) subclinical qualitative defects of platelet function. Combinations of these abnormalities may also occur. In order to decrease the possibility of hemorrhagic complications following openheart procedures, a comprehensive coagulation study has been performed upon all adult patients at The New York Hospital-Cornell Medical Center who were candidates for open-heart surgery over the past 3½ years. Included in the comprehensive coagulation study have been the following determinations: clotting time (Lee-White), bleeding time (Duke), tourniquet test (Rumpel-Leede), clot retraction (Qualitative), platelet estimate (blood smear), platelet count (Phase), fibrinogen (Fowell), fibrinolysis (Euglobin), prothrombin" @default.
- W1974910439 created "2016-06-24" @default.
- W1974910439 creator A5032916526 @default.
- W1974910439 date "1967-03-01" @default.
- W1974910439 modified "2023-09-25" @default.
- W1974910439 title "Thrombocytopathies in Patients With Open-Heart Surgery" @default.
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- W1974910439 doi "https://doi.org/10.1001/archsurg.1967.01330090059015" @default.
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