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- W1974911462 abstract "Local hyperthermia at the fever range was able to promote the migration and activation of Langerhans cells (LCs) in mice [ 1 Ghaznawie M. Papadimitriou J.M. Heenan P.J. The repopulation of murine Langerhans cells after depletion by mild heat injury. Br J Dermatol. 1999; 141: 206-210 Crossref PubMed Scopus (9) Google Scholar , 2 Ostberg J.R. Kabingu E. Repasky E.A. Thermal regulation of dendritic cell activation and migration from skin explants. Int J Hyperthermia. 2003; 19: 520-533 Crossref PubMed Scopus (57) Google Scholar ]. Local hyperthermia was shown to be clinically effective in the treatment of human papillomavirus (HPV) infected skin [ [3] El-Tonsy M.H. Anbar T.E. El-Domyati M. Barakat M. Density of viral particles in pre and post Nd: YAG laser hyperthermia therapy and cryotherapy in plantar warts. Int J Dermatol. 1999; 38: 393-398 Crossref PubMed Scopus (46) Google Scholar ]. Cell-mediated immunity was responsible for the eradication of HPV infected keratinocytes and regression of the warty lesions [ [4] Hong K. Greer C.E. Ketter N. Van Nest G. Paliard X. Isolation and characterization of human papillomavirus type 6-specific T cells infiltrating genital warts. J Virol. 1997; 71: 6427-6432 PubMed Google Scholar ]. Here, we modified a skin organ culture protocol [ [2] Ostberg J.R. Kabingu E. Repasky E.A. Thermal regulation of dendritic cell activation and migration from skin explants. Int J Hyperthermia. 2003; 19: 520-533 Crossref PubMed Scopus (57) Google Scholar ] on condyloma acuminatum (CA), and investigated the effects of above fever range local hyperthermia on the migration and maturation of epidermal LCs, exploring the possible involvement of LCs in immune responses against HPV infection." @default.
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- W1974911462 date "2009-05-01" @default.
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- W1974911462 title "Local hyperthermia could induce migrational maturation of Langerhans cells in condyloma acuminatum" @default.
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- W1974911462 doi "https://doi.org/10.1016/j.jdermsci.2008.12.004" @default.
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