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- W1974920808 abstract "The effect of subcutaneously injected cholecystokinin octapeptide (CCK-8) on amnesia induced by electroconvulsive shock (ECS), CO2 inhalation, or cycloheximide injection was investigated in rats. In normal rats, single administration of CCK-8 had no significant effect on the passive avoidance response. Treatment with ECS, CO2, or cycloheximide markedly decreased the latency of the passive avoidance response, but CCK-8 in doses from 0.1 to 10 μg/kg could prevent the induced amnesia when injected 30 min before the training trials, immediately after foot shock or amnesic treatments, and 30 min before the first retention test. The results indicate that peripheral administration of CCK-8 is effective in preventing amnesia in the rat." @default.
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- W1974920808 date "1986-03-01" @default.
- W1974920808 modified "2023-09-26" @default.
- W1974920808 title "Prevention of experimental amnesia by peripherally administered cholecystokinin octapeptide in the rat" @default.
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- W1974920808 doi "https://doi.org/10.1002/ddr.430070308" @default.
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